Abstract:
Childhood glaucoma represents a heterogenous group of rare ocular conditions that may result in significant sight threatening complications related to elevated intraocular pressure (IOP). It can be classified as either primary or secondary and the latter may have systemic associations. This review will be based on the work of the childhood glaucoma research network (CGRN) and will focus on the diagnosis and management of the most common types of childhood glaucoma. These include primary congenital glaucoma (PCG) and juvenile open angle glaucoma (JOAG) as well as secondary causes of glaucoma associated with non-acquired ocular anomalies (Axenfeld-Rieger anomaly; Peters anomaly and Aniridia), glaucoma associated with systemic disease (Sturge Weber syndrome and Neurofibromatosis), those due to acquired conditions (Uveitic glaucoma, trauma and tumours) and importantly glaucoma following cataract surgery.
摘要:
儿童青光眼代表一组异质性的罕见眼部疾病,可能导致与眼内压(IOP)升高相关的严重威胁视力的并发症。它可以分为主要或次要,后者可能具有系统性关联。这篇综述将基于儿童青光眼研究网络(CGRN)的工作,并将重点关注最常见类型的儿童青光眼的诊断和管理。这些包括原发性先天性青光眼(PCG)和青少年开角型青光眼(JOAG)以及与非获得性眼部异常相关的青光眼的继发原因(Axenfeld-Rieger异常;Peters异常和无虹膜),与全身性疾病相关的青光眼(SturgeWeber综合征和神经纤维瘤病),那些由于后天条件(葡萄膜性青光眼,创伤和肿瘤),并且重要的是白内障手术后的青光眼。