Mesh : Child Chlorides Humans Leishmania tropica Leishmaniasis, Cutaneous / drug therapy Middle Aged Pharmaceutical Preparations Syria

来  源:   DOI:10.4269/ajtmh.21-0962

Abstract:
Cutaneous leishmaniasis (CL) frequently entails chronic skin lesions that heal only slowly. Until now, the available therapeutic options are very limited. Here, we present a case of a 5½-year-old Syrian refugee with two progressive lower-leg skin ulcers caused by Leishmania tropica. The patient received topical treatment with LeiProtect®, a newly developed, hydroxypropylcellulose-based, filmogenic gel containing nontoxic concentrations of pharmaceutical sodium chlorite. The skin lesions completely healed within 8 weeks and did not relapse during 1 year of follow-up, underlining the efficacy of this novel local therapy of CL.
摘要:
皮肤利什曼病(CL)经常引起慢性皮肤病变,只能缓慢愈合。直到现在,可用的治疗选择非常有限。这里,我们介绍了一例5½岁的叙利亚难民,患有两例由热带利什曼原虫引起的小腿皮肤溃疡。患者接受了LeiProtect®的局部治疗,一个新开发的,羟丙基纤维素基,成膜凝胶含有无毒浓度的药物亚氯酸钠。皮损8周内完全愈合,随访1年未复发。强调这种新型局部治疗CL的疗效。
公众号