METHODS: This retrospective study was conducted at Dr. Sardjito General Hospital, Yogyakarta, Indonesia between January 2016 to December 2020. Multivariate analysis was used to assess the correlation between predicting factors and outcomes using logistic regression analysis.
RESULTS: A total of 94 samples were included and analyzed in this study with bacterial meningitis. Neutrophil lymphocyte ratio >5.225 was a significant predictor of mortality in patients with bacterial meningitis with p = 0.004 and risk ratio 10.78. Other factors that were significant predictors of mortality included the pediatric coma scale ≤8 and positive cerebrospinal fluid culture.
CONCLUSIONS: Neutrophil lymphocyte ratio is a statistically significant predictor of mortality in patients with bacterial meningitis, and can be used as a parameter to predict outcomes in patients with bacterial meningitis.
方法:这项回顾性研究是在Sardjito总医院进行的,日惹,印度尼西亚2016年1月至2020年12月。多因素分析用于使用逻辑回归分析评估预测因素与结果之间的相关性。
结果:本研究共纳入94个样本,并对其进行分析。中性粒细胞淋巴细胞比率>5.225是细菌性脑膜炎患者死亡率的重要预测因子,p=0.004,风险比10.78。其他重要的死亡率预测因素包括小儿昏迷评分≤8和脑脊液培养阳性。
结论:中性粒细胞淋巴细胞比率是细菌性脑膜炎患者死亡率的统计学显著预测指标,并且可以用作预测细菌性脑膜炎患者预后的参数。