Abstract：
TAFRO syndrome is a peculiar and rare type of multi-centric Castleman\'s disease which contained a series of symptoms such as thrombocytopenia (T), anasarca (A), fever (F), reticulin fibrosis (R), and organomegaly (O). Here we provide a case of TAFRO syndrome with the manifestation of fatigue, abdominal distension, and low fever at primary diagnosis, characterized by multiple lymphadenopathy of superficial mediastinal and retroperitoneal lymph nodes, and it was finally confirmed by lymph node biopsy. The patient recovered speedy after receiving CHOP chemotherapy. In this case report, the patient has a history of dust-exposure and hepatitis B virus infection, which may be potentially related to the disease. In addition, this case suggests the importance of pathological biopsy of complete lymph nodes in diagnostic process.
摘要：
TAFRO综合征是一种特殊而罕见的多中心型Castleman病，它具有血小板减少症(T)等一系列症状，anasarca(A),发烧（F），网织蛋白纤维化（R），和器官肿大（O）。在这里，我们提供了一个表现为疲劳的TAFRO综合征，腹胀,在初级诊断时低烧，以纵隔浅层和腹膜后淋巴结多发淋巴结为特征，最后通过淋巴结活检证实。患者接受CHOP化疗后迅速恢复。在这个案例报告中,患者有粉尘暴露和乙型肝炎病毒感染史，这可能与疾病有关。此外,此病例提示完整淋巴结的病理活检在诊断过程中的重要性。
