PDF(Pubmed)
Abstract：
Fibrocytes are hematopoietic-derived cells that directly contribute to tissue fibrosis by producing collagen following injury, during disease, and with aging. The lack of a fibrocyte-specific marker has led to the use of multiple strategies for identifying these cells in vivo. This review will detail how past studies were performed, report their findings, and discuss their strengths and limitations. The motivation is to identify opportunities for further investigation and promote the adoption of best practices during future study design.
摘要：
纤维细胞是造血来源的细胞，通过在损伤后产生胶原直接导致组织纤维化，在疾病期间，随着衰老。缺乏纤维细胞特异性标记已导致使用多种策略在体内鉴定这些细胞。这篇综述将详细介绍过去的研究是如何进行的，报告他们的发现，并讨论它们的优点和局限性。动机是确定进一步调查的机会，并在未来的研究设计中促进最佳实践的采用。
