关键词: 2-hydroxyglutarate cancer stem cells chemotherapy differentiation enasidenib isocitrate dehydrogenase ivosidenib targeted therapy therapy responses
Mesh : Antineoplastic Agents / pharmacology Cell Differentiation / drug effects Enzyme Inhibitors / pharmacology Humans Isocitrate Dehydrogenase / antagonists & inhibitors genetics metabolism Leukemia, Myeloid, Acute / drug therapy metabolism pathology Mutation Neoplastic Stem Cells / drug effects metabolism
来 源: DOI:10.1369/00221554211062499