Abstract：
OBJECTIVE: Herpes simplex virus (HSV) infections have been reported in 60% to 95% of the adult population worldwide, making them one of the most common infectious conditions globally. HSV-1 and HSV-2 cause severe disease in immunocompromised patients. Therefore, the aim of this study was to provide information that could be used to reduce the incidence of genital herpes caused by HSV-1 and HSV-2.
METHODS: From September 2018 to December 2020, 59,381 specimens were collected from outpatients across primary and secondary hospitals in Korea who requested U2Bio (Korea) to conduct molecular biological testing of their samples for sexually transmitted infections. In this study, the positivity rates of HSV-1 and HSV-2 were analyzed according to age, sex, and specimen type.
RESULTS: In the age-specific analysis of HSV-1, the highest positivity rate (0.58%) was observed in patients under 19 years of age, whereas the lowest positivity rate (0.08%) was observed in patients aged over 70 years. In the age-specific analysis of HSV-2, the highest positivity rate (2.53%) was likewise observed in patients under 19 years of age.
CONCLUSIONS: Our study identified differences in the infection rates of HSV-1 and HSV-2 depending on patients\' sex and age. These differences will be useful for improving disease prevention and control measures for HSV-1 and HSV-2.
METHODS: From September 2018 to December 2020, 59,381 specimens were collected from outpatients across primary and secondary hospitals in Korea who requested U2Bio (Korea) to conduct molecular biological testing of their samples for sexually transmitted infections. In this study, the positivity rates of HSV-1 and HSV-2 were analyzed according to age, sex, and specimen type.
RESULTS: In the age-specific analysis of HSV-1, the highest positivity rate (0.58%) was observed in patients under 19 years of age, whereas the lowest positivity rate (0.08%) was observed in patients aged over 70 years. In the age-specific analysis of HSV-2, the highest positivity rate (2.53%) was likewise observed in patients under 19 years of age.
CONCLUSIONS: Our study identified differences in the infection rates of HSV-1 and HSV-2 depending on patients\' sex and age. These differences will be useful for improving disease prevention and control measures for HSV-1 and HSV-2.
摘要：
目的：据报道，全世界60％至95％的成年人群感染了单纯疱疹病毒（HSV）。使它们成为全球最常见的传染病之一。HSV-1和HSV-2在免疫受损患者中引起严重疾病。因此,本研究的目的是提供可用于降低由HSV-1和HSV-2引起的生殖器疱疹发生率的信息.
方法：从2018年9月至2020年12月，从韩国一级和二级医院的门诊患者中收集了59,381份样本，他们要求U2Bio（韩国）对其样本进行性传播感染的分子生物学检测。在这项研究中,根据年龄分析HSV-1和HSV-2的阳性率，性别,和标本类型。
结果：在HSV-1的年龄特异性分析中，在19岁以下的患者中观察到最高的阳性率（0.58％），而在70岁以上的患者中观察到的阳性率最低（0.08％）。在HSV-2的年龄特异性分析中，在19岁以下的患者中同样观察到最高的阳性率（2.53％）。
结论：我们的研究发现，根据患者的性别和年龄，HSV-1和HSV-2感染率存在差异。这些差异将有助于改善HSV-1和HSV-2的疾病预防和控制措施。
方法：从2018年9月至2020年12月，从韩国一级和二级医院的门诊患者中收集了59,381份样本，他们要求U2Bio（韩国）对其样本进行性传播感染的分子生物学检测。在这项研究中,根据年龄分析HSV-1和HSV-2的阳性率，性别,和标本类型。
结果：在HSV-1的年龄特异性分析中，在19岁以下的患者中观察到最高的阳性率（0.58％），而在70岁以上的患者中观察到的阳性率最低（0.08％）。在HSV-2的年龄特异性分析中，在19岁以下的患者中同样观察到最高的阳性率（2.53％）。
结论：我们的研究发现，根据患者的性别和年龄，HSV-1和HSV-2感染率存在差异。这些差异将有助于改善HSV-1和HSV-2的疾病预防和控制措施。
