关键词: C. gattii Cryptococcus spp. cryptococcal meningitis cryptococcosis immune reconstitution inflammatory syndrome C. gattii Cryptococcus spp. cryptococcal meningitis cryptococcosis immune reconstitution inflammatory syndrome

Mesh : Australia / epidemiology Cryptococcosis / diagnosis drug therapy Cryptococcus gattii Cryptococcus neoformans Hematology Humans Saccharomyces cerevisiae

来  源:   DOI:10.1111/imj.15590

Abstract:
Cryptococcosis caused by the Cryptococcus neoformans-Cryptococcus gattii complex is an important opportunistic infection in people with immunodeficiency, including in the haematology/oncology setting. This may manifest clinically as cryptococcal meningitis or pulmonary cryptococcosis, or be detected incidentally by cryptococcal antigenemia, a positive sputum culture or radiological imaging. Non-Candida, non-Cryptococcus spp. rare yeast fungaemia are increasingly common in this population. These consensus guidelines aim to provide clinicians working in the Australian and New Zealand haematology/oncology setting with clear guiding principles and practical recommendations for the management of cryptococcosis, while also highlighting important and emerging rare yeast infections and their recommended management.
摘要:
由新生隐球菌-加替隐球菌复合体引起的隐球菌病是免疫缺陷患者的重要机会性感染,包括血液学/肿瘤学。这可能在临床上表现为隐球菌性脑膜炎或肺隐球菌病,或者被隐球菌抗原血症偶然发现,痰培养或放射成像阳性。非念珠菌,非隐球菌属。罕见的酵母真菌血症在这个人群中越来越常见。这些共识指南旨在为在澳大利亚和新西兰血液科/肿瘤科工作的临床医生提供明确的指导原则和实际建议,以管理隐球菌病。同时还强调了重要的和新兴的罕见酵母菌感染及其推荐的管理。
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