Mesh : Animals Blood Circulation / drug effects Blood Glucose / drug effects metabolism Bone Density / drug effects Carica / chemistry Computational Biology Drugs, Chinese Herbal / chemistry pharmacology Endocrine Glands / drug effects physiology Immunity / drug effects Lactic Acid / blood Male Metabolism / drug effects Models, Animal Oxidative Stress / drug effects Panax / chemistry Physical Exertion / drug effects Rats Rats, Sprague-Dawley

来  源:   DOI:10.1155/2021/9934107   PDF(Pubmed)

Abstract:
OBJECTIVE: To determine whether feeding CircuCare to rats improves blood circulation, metabolism, immune regulation, endocrine activity, and oxidative stress.
METHODS: 28 eight-week-old male Sprague-Dawley rats were evenly randomized into control and experimental groups. The control group was fed with ordinary drinking water, while the experimental group was fed with CircuCare at a daily dose of 93.75 mg per 300 g of body weight over eight weeks. Both groups were subjected to a swimming test, and blood samples were taken to observe any variations in various biochemical parameters before and after the test. Key Findings. The experimental group\'s mean swimming exhaustion duration was 53.2% longer and had a significantly higher lactic acid removal ratio. Their mean prostaglandin E2 level and mean glucose, cortisol, and glutathione level (30 minutes after swimming test) were also significantly higher. No undesirable impacts from CircuCare relating to general blood biochemistry values and bone mineral density were reported.
CONCLUSIONS: The present results show that CircuCare can be safely used to increase stamina and exercise capability, expedite the metabolism of lactic acid, accelerate muscle repair, and promote the antioxidant activity of cells in rats.
摘要:
目的:确定给大鼠喂食CircuitCare是否能改善血液循环,新陈代谢,免疫调节,内分泌活动,和氧化应激。
方法:将28只8周龄雄性SD大鼠随机分为对照组和实验组。对照组饲喂普通饮用水,而实验组在八周内以每300克体重93.75毫克的日剂量饲喂Circuit。两组都进行了游泳测试,和血液样本,以观察测试前后各种生化参数的任何变化。关键发现。实验组的平均游泳力竭持续时间延长了53.2%,并且乳酸去除率明显更高。他们的平均前列腺素E2水平和平均葡萄糖,皮质醇,谷胱甘肽水平(游泳试验后30分钟)也显著升高。没有报道CircuitCare对一般血液生化值和骨矿物质密度的不良影响。
结论:目前的结果表明,CircuitCare可以安全地用于增加耐力和运动能力,加快乳酸的代谢,加速肌肉修复,并促进大鼠细胞的抗氧化活性。
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