PDF(Pubmed)
Abstract：
We describe a case of Sjögren\'s syndrome-associated trigeminal neuropathy with mandibular nerve enhancement at the foramen ovale and Gasserian ganglion (Meckel\'s cave) in a patient with a prior history of breast cancer. We also explore the differential diagnosis of trigeminal neuropathy associated with mandibular nerve involvement at the foramen ovale and exclude other diseases such as Sjögren\'s syndrome or perineurial invasion as a result of various carcinomas. We emphasize the importance of an investigative triad of searching for a local head-and-neck malignancy that may metastasize by perineural spread or invasion, excluding a distant malignancy or paraneoplastic phenomenon and ruling out an autoimmune etiology such as Sjögren\'s syndrome. In the process, we briefly outline the basic immunopathologic processes.
摘要：
我们描述了一例与Sjögren综合征相关的三叉神经病变，在卵圆孔和Gasserian神经节（Meckel洞穴）下颌神经增强。我们还探讨了与卵圆孔下颌神经受累相关的三叉神经病变的鉴别诊断，并排除了其他疾病，例如干燥综合征或各种癌引起的神经周浸润。我们强调调查三合会的重要性，即寻找可能通过神经周传播或侵入而转移的局部头颈部恶性肿瘤，排除远处恶性肿瘤或副肿瘤现象，排除自身免疫性病因，如干燥综合征。在这个过程中,我们简要概述了基本的免疫病理过程。
