关键词: Genitourinary syndrome of menopause drug facts box interdisciplinary consensus personalized treatment prasterone vaginal estrogen

Mesh : Atrophy / drug therapy Consensus Dehydroepiandrosterone / therapeutic use Female Female Urogenital Diseases / drug therapy Humans Menopause Switzerland Syndrome Vagina / pathology

来  源:   DOI:10.1080/13697137.2021.2008894

Abstract:
Genitourinary syndrome of menopause (GSM) has a significantly negative impact on affected women\'s lives. However, despite the increasing number of GSM treatment options (e.g. non-hormonal vaginal products, vaginal hormones [estrogens], dehydroepiandrosterone [DHEA; prasterone], vaginal laser therapy, oral ospemifene), many women remain untreated. The goal of the Swiss interdisciplinary GSM consensus meeting was to develop tools for GSM management in daily practice: a GSM management algorithm (personalized medicine); a communication tool for vaginal DHEA (drug facts box); and a communication tool for understanding regulatory authorities and the discrepancy between scientific data and package inserts. The acceptance and applicability of such tools will be further investigated.
摘要:
更年期泌尿生殖系统综合征(GSM)对女性的生活有显著的负面影响。然而,尽管越来越多的GSM治疗选择(例如非激素阴道产品,阴道激素[雌激素],脱氢表雄酮[DHEA;praestone],阴道激光治疗,口服奥培米芬),许多妇女仍未得到治疗。瑞士跨学科GSM共识会议的目标是在日常实践中开发GSM管理工具:GSM管理算法(个性化医疗);用于阴道DHEA(药物事实框)的通信工具;以及用于了解监管机构以及科学数据与包装之间差异的通信工具。将进一步研究此类工具的接受度和适用性。
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