关键词: AD, Alzheimer disease ALARM NMR, a La assay to detect reactive molecules by nuclear magnetic resonance Biochemical experiment CADD, computer-aided drug design technology CoA, coenzyme A EGFR, epidermal growth factor receptor Fair trial strategy GSH, glutathione HER2, human epidermal growth factor receptor 2 HTS, high-throughput screening In silico filtering LC−MS, liquid chromatography−mass spectrometry MTDLs, multitarget-directed ligands Multitarget-directed ligands PAINS suspects PAINS, pan-assay interference compounds QSAR, quantitative structure–activity relationship ROS, radicals and oxygen reactive species
来 源:
DOI:10.1016/j.apsb.2021.02.023
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