PDF(Pubmed)
Abstract：
Homicide combined with subsequent suicide of the perpetrator is a particular form of interpersonal violence and, at the same time, a manifestation of extreme aggression directed against oneself. Despite the relatively well-described individual acts of homicide and suicide, both in terms of psychopathology and law, acts of homicide and subsequent suicide committed by the same person are not well-studied phenomena. The importance of emotional factors, including the influence of mental state deviations (psychopathology), on this phenomenon, is discussed in the literature, but still there is relatively little data with which to attempt neuropathological assessments of the brains of suicide killers. This paper is dedicated to the issue based on the neuropathological studies performed.
We analyzed a group of murder-suicides using histochemical and immunohistochemical methods.
The results of our research indicate the presence of neurodegenerative changes including multiple deposits of ß-amyloid in the form of senile/amyloid plaques and perivascular diffuse plaques.
Neurodegenerative changes found in the analyzed brains of suicide killers may provide an interesting starting point for a number of analyses. The presence of neurodegenerative changes at such a young age in some murderers may suggest preclinical lesions that affect cognitive functions and are associated with depressed moods.
We analyzed a group of murder-suicides using histochemical and immunohistochemical methods.
The results of our research indicate the presence of neurodegenerative changes including multiple deposits of ß-amyloid in the form of senile/amyloid plaques and perivascular diffuse plaques.
Neurodegenerative changes found in the analyzed brains of suicide killers may provide an interesting starting point for a number of analyses. The presence of neurodegenerative changes at such a young age in some murderers may suggest preclinical lesions that affect cognitive functions and are associated with depressed moods.
摘要：
凶杀与肇事者随后的自杀相结合是一种特殊的人际暴力形式，同时,对自己进行极端侵略的表现。尽管杀人和自杀的个人行为描述相对良好，在精神病理学和法律方面，由同一人犯下的杀人行为和随后的自杀行为不是很好的研究现象。情感因素的重要性，包括精神状态偏差(精神病理学)的影响，在这种现象上，在文献中讨论过，但是仍然有相对较少的数据来尝试对自杀杀手的大脑进行神经病理学评估。本文致力于基于神经病理学研究的问题。
我们使用组织化学和免疫组织化学方法分析了一组谋杀自杀。
我们的研究结果表明存在神经退行性变化，包括β-淀粉样蛋白以衰老/淀粉样蛋白斑块和血管周围弥漫性斑块的形式沉积。
在分析的自杀杀手大脑中发现的神经退行性变化可能为许多分析提供了一个有趣的起点。在一些杀人犯中，在如此年轻的年龄存在神经退行性变化可能表明影响认知功能并与抑郁情绪有关的临床前病变。
我们使用组织化学和免疫组织化学方法分析了一组谋杀自杀。
我们的研究结果表明存在神经退行性变化，包括β-淀粉样蛋白以衰老/淀粉样蛋白斑块和血管周围弥漫性斑块的形式沉积。
在分析的自杀杀手大脑中发现的神经退行性变化可能为许多分析提供了一个有趣的起点。在一些杀人犯中，在如此年轻的年龄存在神经退行性变化可能表明影响认知功能并与抑郁情绪有关的临床前病变。
