PDF(Pubmed)
Abstract：
Glucocorticoids are used as a first-line treatment for severe alcoholic hepatitis, and albumin reduces both the number of hospitalizations and mortality in patients with decompensated cirrhosis. However, for acute-on-chronic liver failure (ACLF), there is no definitive evidence that glucocorticoid therapy is beneficial. In this case report, we describe a male patient who developed into ACLF based on alcoholic cirrhosis, whose symptoms and clinical indicators continued to deteriorate after initial symptomatic treatment. The patient\'s condition gradually improved after low-dose glucocorticoid therapy, and long-term albumin supplementation resulted in a satisfactory outcome.
摘要：
糖皮质激素被用作严重酒精性肝炎的一线治疗，白蛋白降低了失代偿期肝硬化患者的住院次数和死亡率。然而,用于慢性急性肝衰竭（ACLF），没有明确的证据表明糖皮质激素治疗是有益的.在这个案例报告中,我们描述了一名男性患者因酒精性肝硬化发展为ACLF，最初对症治疗后，其症状和临床指标继续恶化。小剂量糖皮质激素治疗后病情逐渐好转,长期补充白蛋白的结果令人满意.
