关键词: Nasal spray Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) inactivation nasopharynx oral cavity oral spray quantitative suspension test transmission

来  源:   DOI:10.1016/j.jhin.2021.10.019   PDF(Pubmed)

Abstract:
The highest viral loads of the newly emerged Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) are detectable in the oral cavity, thus, a potential reduction of infectious virus by nasal sprays could lower transmission. Therefore, the inactivation capacity of nine nasal and oral sprays was evaluated according to EN 14476. One nasal spray based on sodium hypochlorite and an oral spray containing essential oils reduced viral titres between 2 to 3 orders of magnitude. Although clinical data is still sparse, nasal and oral sprays display a more convenient application for elderly people or those who are unable to rinse/gargle.
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