PDF(Pubmed)
Abstract：
UNASSIGNED: Endobronchial ultrasound (EBUS)-guided fine-needle aspiration cytology (FNAC) is recommended for diagnosing bronchial neoplasms and evaluating mediastinal lymph nodes. However, it may not be possible to subtype or definitely categorize many bronchial neoplasms on FNAC smears alone. Obtaining adequate diagnostic material is often a problem. In such cases, cell blocks made from FNAC material may serve as a useful adjunct. Aim: To study the value and limitations of cell blocks in adding diagnostic information to EBUS guided FNAC smears.
UNASSIGNED: One hundred and eighty-five cases of EBUS guided FNAC having concomitant cell blocks were reviewed. The cases were evaluated for the extent of adequacy, of definite benign/malignant categorization and of definite subtyping in malignant tumors in these cases. The proportion of cases in which cell blocks added information to FNAC smears alone for the above parameters were calculated.
UNASSIGNED: Cell blocks provided additional information in 31 out of 185 cases. Cell blocks were necessary for subtyping 24/59 malignant tumors, definite categorization into benign and malignant in 10/140 adequate samples, and increasing adequacy in 6/185 total samples. A total of 45 samples were inadequate in spite of adding information from cell blocks to smears.
UNASSIGNED: Cell blocks added clinically significant information to EBUS guided FNAC and should be used routinely. To make it more useful, alternative methods of cell block preparation (including proprietary methods) may be evaluated.
UNASSIGNED: One hundred and eighty-five cases of EBUS guided FNAC having concomitant cell blocks were reviewed. The cases were evaluated for the extent of adequacy, of definite benign/malignant categorization and of definite subtyping in malignant tumors in these cases. The proportion of cases in which cell blocks added information to FNAC smears alone for the above parameters were calculated.
UNASSIGNED: Cell blocks provided additional information in 31 out of 185 cases. Cell blocks were necessary for subtyping 24/59 malignant tumors, definite categorization into benign and malignant in 10/140 adequate samples, and increasing adequacy in 6/185 total samples. A total of 45 samples were inadequate in spite of adding information from cell blocks to smears.
UNASSIGNED: Cell blocks added clinically significant information to EBUS guided FNAC and should be used routinely. To make it more useful, alternative methods of cell block preparation (including proprietary methods) may be evaluated.
摘要：
■建议支气管内超声（EBUS）引导的细针穿刺细胞学检查（FNAC）用于诊断支气管肿瘤和评估纵隔淋巴结。然而,仅在FNAC涂片上可能无法对许多支气管肿瘤进行亚型或明确分类。获得足够的诊断材料通常是一个问题。在这种情况下,由FNAC材料制成的电池块可以用作有用的附属物。目的：研究细胞块在EBUS指导的FNAC涂片中添加诊断信息的价值和局限性。
■回顾了185例EBUS引导的FNAC伴随细胞块。对这些病例的充分性进行了评估，在这些病例中，恶性肿瘤的明确良性/恶性分类和明确的亚型。对于上述参数，计算了细胞块仅向FNAC涂片添加信息的病例比例。
■细胞块在185例病例中提供了31例的额外信息。细胞块是对24/59恶性肿瘤进行分型所必需的，在10/140充足的样本中明确分为良性和恶性，并增加6/185总样本的充分性。尽管将细胞块的信息添加到涂片中，但总共有45个样品不足。
■细胞块为EBUS指导的FNAC增加了临床重要信息，应常规使用。为了让它更有用，可以评估细胞块制备的替代方法(包括专有方法)。
■回顾了185例EBUS引导的FNAC伴随细胞块。对这些病例的充分性进行了评估，在这些病例中，恶性肿瘤的明确良性/恶性分类和明确的亚型。对于上述参数，计算了细胞块仅向FNAC涂片添加信息的病例比例。
■细胞块在185例病例中提供了31例的额外信息。细胞块是对24/59恶性肿瘤进行分型所必需的，在10/140充足的样本中明确分为良性和恶性，并增加6/185总样本的充分性。尽管将细胞块的信息添加到涂片中，但总共有45个样品不足。
■细胞块为EBUS指导的FNAC增加了临床重要信息，应常规使用。为了让它更有用，可以评估细胞块制备的替代方法(包括专有方法)。
