关键词: IRBDSG PSG RWA iRBD iRWA prodromal RBD

Mesh : Humans Movement Polysomnography Prodromal Symptoms REM Sleep Behavior Disorder / diagnosis Sleep, REM / physiology

来  源:   DOI:10.1093/sleep/zsab257

Abstract:
Video-polysomnography (v-PSG) is essential for diagnosing rapid eye movement (REM) sleep behavior disorder (RBD). Although there are current American Academy of Sleep Medicine standards to diagnose RBD, several aspects need to be addressed to achieve harmonization across sleep centers. Prodromal RBD is a stage in which symptoms and signs of evolving RBD are present, but do not yet meet established diagnostic criteria for RBD. However, the boundary between prodromal and definite RBD is still unclear. As a common effort of the Neurophysiology Working Group of the International RBD Study Group, this manuscript addresses the need for comprehensive and unambiguous v-PSG recommendations to diagnose RBD and identify prodromal RBD. These include: (1) standardized v-PSG technical settings; (2) specific considerations for REM sleep scoring; (3) harmonized methods for scoring REM sleep without atonia; (4) consistent methods to analyze video and audio recorded during v-PSGs and to classify movements and vocalizations; (5) clear v-PSG guidelines to diagnose RBD and identify prodromal RBD. Each section follows a common template: The current recommendations and methods are presented, their limitations are outlined, and new recommendations are described. Finally, future directions are presented. These v-PSG recommendations are intended for both practicing clinicians and researchers. Classification and quantification of motor events, RBD episodes, and vocalizations are however intended for research purposes only. These v-PSG guidelines will allow collection of homogeneous data, providing objective v-PSG measures and making future harmonized multicentric studies and clinical trials possible.
摘要:
视频多导睡眠图(v-PSG)对于诊断快速眼动(REM)睡眠行为障碍(RBD)至关重要。尽管目前美国睡眠医学学会有诊断RBD的标准,需要解决几个方面来实现跨睡眠中心的协调。前驱RBD是RBD演变的症状和体征存在的阶段,但尚未达到RBD的既定诊断标准。然而,前驱RBD与确定RBD之间的界限尚不清楚。作为国际RBD研究小组神经生理学工作组的共同努力,该手稿满足了全面且明确的v-PSG建议以诊断RBD和识别前驱RBD的需要.其中包括:(1)标准化的v-PSG技术设置;(2)REM睡眠评分的具体考虑因素;(3)对无张力的REM睡眠评分的统一方法;(4)分析v-PSG期间记录的视频和音频并对运动和发声进行分类的一致方法;(5)明确的v-PSG指南,以诊断RBD并识别前驱RBD。每个部分都遵循一个通用模板:介绍了当前的建议和方法,概述了它们的局限性,并描述了新的建议。最后,提出了未来的方向。这些v-PSG建议适用于执业临床医生和研究人员。运动事件的分类和量化,RBD发作,然而,发声仅用于研究目的。这些v-PSG指南将允许收集同质数据,提供客观的v-PSG措施,使未来的协调多中心研究和临床试验成为可能。
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