甘草查尔酮 A 通过调节 T 淋巴细胞 ORAI1 和 K + 通道的抗炎作用.
关键词: anti-inflammatory effect calcium-activated potassium channel calcium-release-activated calcium channel protein 1 licochalcone A store-operated calcium entry voltage-gated potassium channel
Mesh : Anti-Inflammatory Agents / pharmacology Calcium / metabolism Calcium Signaling Chalcones / pharmacology Gene Expression Regulation / drug effects HEK293 Cells Humans Intermediate-Conductance Calcium-Activated Potassium Channels / antagonists & inhibitors genetics metabolism Jurkat Cells Kv1.3 Potassium Channel / antagonists & inhibitors genetics metabolism ORAI1 Protein / antagonists & inhibitors genetics metabolism T-Lymphocytes / drug effects immunology metabolism
来 源:
DOI:10.3390/ijms221910847
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