Abstract：
Vitiligo is a chronic pigmentary skin disorder that results in white, hypopigmented macules and patches. It causes a considerable psychological and emotional burden on the affected individuals and their families. Several therapeutic options have been employed in vitiligo including topical and oral drugs, surgical techniques, and phototherapy which is considered the cornerstone treatment. Different wavelengths and modalities are available, but narrowband UVB (NB-UVB) is considered the safest and the most effective phototherapy alternative. NB-UVB acts on multiple steps in vitiligo pathogenesis, and it is capable of inducing stabilization and repigmentation of vitiligo lesions. Technological advances have led to the development of both new phototherapy devices and new medical and surgical therapeutic options that can be combined with phototherapy to achieve optimal results. There is no standard treatment, and individual patient and disease characteristics should be considered. We review the current evidence in what concerns UVB phototherapy for vitiligo treatment, including novel combination treatments that may help to provide the best care for these patients.
摘要：
白癜风是一种慢性色素性皮肤病，导致白色，色素沉着斑和斑块。它给受影响的个人及其家人造成了相当大的心理和情感负担。白癜风已经采用了几种治疗方法，包括局部和口服药物，外科技术,和被认为是基石治疗的光疗。不同的波长和模式是可用的，但窄带UVB（NB-UVB）被认为是最安全和最有效的光疗选择。NB-UVB在白癜风发病机制中的多步骤作用，它能够诱导白癜风病变的稳定和色素沉着。技术进步导致了新的光疗设备以及新的医疗和外科治疗选择的开发，这些选择可以与光疗相结合以达到最佳效果。没有标准的治疗方法,应考虑个体患者和疾病特征。我们回顾了目前关于UVB光疗治疗白癜风的证据，包括可能有助于为这些患者提供最佳护理的新型联合治疗。
