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Abstract：
OBJECTIVE: To investigate the impact of single-vision spectacle use on myopia progression in children with low myopia.
METHODS: MYOSOTIS is a prospective myopia screening survey including all 46 primary and junior high schools in two districts of Hangzhou, China. After 1-to-1 propensity score matching (PSM), 1,685 pairs of students with low myopia were included. Group 1 was composed of 1,685 non-spectacle users at baseline, and group 2 consisted of 1,685 spectacle wearers at both survey rounds. Refraction was examined by noncycloplegic autorefraction and mean spherical equivalent refraction (SER) of both eyes was analyzed. Myopia progression was measured by average rate of change in SER (r∆SER) between two survey rounds and compared between the two groups.
RESULTS: After PSM, no significant difference in age, sex ratio, SER, and uncorrected visual acuity (VA) between the two groups was found at baseline. For myopic progression, r∆SER showed no significant difference between the two groups (- 0.67 ± 0.97 versus - 0.69 ± 0.81 diopter/year, P = 0.448). After adjusting for age, sex, SER, and VA, the difference in r∆SER between the two groups was not significant (- 0.031, 95% CI - 0.089 ~ 0.028 diopter/year, P = 0.302). In the subgroup analyses stratified by age and SER, and in the sensitivity analyses by eye side, there was still no significant difference in myopia progression between the two groups.
CONCLUSIONS: Our study indicates that single-vision spectacle use has no impact on myopia progression in children with low myopia. Spectacles are recommended in children with low myopia if their visual acuity has interfered with the daily life.
METHODS: MYOSOTIS is a prospective myopia screening survey including all 46 primary and junior high schools in two districts of Hangzhou, China. After 1-to-1 propensity score matching (PSM), 1,685 pairs of students with low myopia were included. Group 1 was composed of 1,685 non-spectacle users at baseline, and group 2 consisted of 1,685 spectacle wearers at both survey rounds. Refraction was examined by noncycloplegic autorefraction and mean spherical equivalent refraction (SER) of both eyes was analyzed. Myopia progression was measured by average rate of change in SER (r∆SER) between two survey rounds and compared between the two groups.
RESULTS: After PSM, no significant difference in age, sex ratio, SER, and uncorrected visual acuity (VA) between the two groups was found at baseline. For myopic progression, r∆SER showed no significant difference between the two groups (- 0.67 ± 0.97 versus - 0.69 ± 0.81 diopter/year, P = 0.448). After adjusting for age, sex, SER, and VA, the difference in r∆SER between the two groups was not significant (- 0.031, 95% CI - 0.089 ~ 0.028 diopter/year, P = 0.302). In the subgroup analyses stratified by age and SER, and in the sensitivity analyses by eye side, there was still no significant difference in myopia progression between the two groups.
CONCLUSIONS: Our study indicates that single-vision spectacle use has no impact on myopia progression in children with low myopia. Spectacles are recommended in children with low myopia if their visual acuity has interfered with the daily life.
摘要：
目的：探讨使用单视眼镜对低度近视儿童近视进展的影响。
方法：MYOSOTIS是一项前瞻性近视筛查调查，包括杭州两个区的所有46所小学和初中，中国。在1对1倾向得分匹配(PSM)后，纳入1,685对低近视学生。第一组由基线时的1685名非眼镜用户组成，第2组包括1,685名眼镜配戴者在两轮调查中。通过非睫状肌麻痹自屈光检查屈光度，并分析了双眼的平均球面等效屈光度（SER）。通过两轮调查之间的平均SER变化率（rΔSER）来测量近视进展，并比较两组之间的差异。
结果：PSM后，年龄无显著差异,性别比例,SER,在基线时发现两组之间的未矫正视力（VA）。对于近视进展，rΔSER在两组之间没有显着差异（-0.67±0.97与-0.69±0.81屈光度/年，P=0.448）。在调整了年龄之后,性别,SER,VA,两组间rΔSER差异无显著性(-0.031,95%CI-0.089~0.028屈光度/年,P=0.302）。在按年龄和SER分层的亚组分析中，在眼睛侧的灵敏度分析中，两组间近视进展仍无显著差异.
结论：我们的研究表明，使用单视眼镜对低近视儿童的近视进展没有影响。如果低近视儿童的视力干扰了日常生活，建议使用眼镜。
方法：MYOSOTIS是一项前瞻性近视筛查调查，包括杭州两个区的所有46所小学和初中，中国。在1对1倾向得分匹配(PSM)后，纳入1,685对低近视学生。第一组由基线时的1685名非眼镜用户组成，第2组包括1,685名眼镜配戴者在两轮调查中。通过非睫状肌麻痹自屈光检查屈光度，并分析了双眼的平均球面等效屈光度（SER）。通过两轮调查之间的平均SER变化率（rΔSER）来测量近视进展，并比较两组之间的差异。
结果：PSM后，年龄无显著差异,性别比例,SER,在基线时发现两组之间的未矫正视力（VA）。对于近视进展，rΔSER在两组之间没有显着差异（-0.67±0.97与-0.69±0.81屈光度/年，P=0.448）。在调整了年龄之后,性别,SER,VA,两组间rΔSER差异无显著性(-0.031,95%CI-0.089~0.028屈光度/年,P=0.302）。在按年龄和SER分层的亚组分析中，在眼睛侧的灵敏度分析中，两组间近视进展仍无显著差异.
结论：我们的研究表明，使用单视眼镜对低近视儿童的近视进展没有影响。如果低近视儿童的视力干扰了日常生活，建议使用眼镜。
