Abstract：
OBJECTIVE: The purpose of this systematic review was to evaluate the survival rate, biological complications, technical complications, and clinical behavior of single crowns supported by teeth made up in monolithic zirconia with CAD/CAM technology.
METHODS: An extensive electronic search was conducted through Medline/PubMed, Embase, and Cochrane Library databases. Additional manual search was performed on the references of included articles to identify relevant publications. Two reviewers independently performed the selection and electronic and manual search.
RESULTS: From nine articles included, there was a total of 594 participants and 1657 single-tooth restorations with a mean exposure time of 1.07 years, and follow-up period between 0.3 and 2.1 years. All studies showed a moderate level of quality, with a consequent moderate possibility of associated bias, using the Newcastle-Ottawa Scale (NOS), with survival rate (SR) ranging between 91% to 100%. Bleeding on probing (BOP) were reported with an average value of 29.12%. Marginal integrity showed high success rate values for the observation periods, except for one that included patients with bruxism which obtained a SR of 31.60%. Failures and/or fractures, mostly total and requiring replacement, were observed in three studies. Linear regression showed that there was no statistical correlation between survival rate and type of cementation and the average years of follow-up (p=0.730 e p=0.454). There was high heterogeneity between studies (I2 = 93.74% and Q = 79.672).
CONCLUSIONS: Within the limitation of this study, monolithic zirconia might be considered as a possible option for restoring single crowns, especially in the posterior zone.
METHODS: An extensive electronic search was conducted through Medline/PubMed, Embase, and Cochrane Library databases. Additional manual search was performed on the references of included articles to identify relevant publications. Two reviewers independently performed the selection and electronic and manual search.
RESULTS: From nine articles included, there was a total of 594 participants and 1657 single-tooth restorations with a mean exposure time of 1.07 years, and follow-up period between 0.3 and 2.1 years. All studies showed a moderate level of quality, with a consequent moderate possibility of associated bias, using the Newcastle-Ottawa Scale (NOS), with survival rate (SR) ranging between 91% to 100%. Bleeding on probing (BOP) were reported with an average value of 29.12%. Marginal integrity showed high success rate values for the observation periods, except for one that included patients with bruxism which obtained a SR of 31.60%. Failures and/or fractures, mostly total and requiring replacement, were observed in three studies. Linear regression showed that there was no statistical correlation between survival rate and type of cementation and the average years of follow-up (p=0.730 e p=0.454). There was high heterogeneity between studies (I2 = 93.74% and Q = 79.672).
CONCLUSIONS: Within the limitation of this study, monolithic zirconia might be considered as a possible option for restoring single crowns, especially in the posterior zone.
摘要：
目的：本系统评价的目的是评估生存率，生物并发症，技术并发症,以及使用CAD/CAM技术由整体式氧化锆组成的牙齿支撑的单冠的临床行为。
方法：通过Medline/PubMed进行了广泛的电子搜索，Embase,和Cochrane图书馆数据库。对所收录文章的参考文献进行了其他手动搜索，以确定相关出版物。两名审阅者独立执行选择以及电子和手动搜索。
结果：从包括的九篇文章中，共有594名参与者和1657个单牙修复体，平均暴露时间为1.07年，随访期在0.3至2.1年之间。所有研究都显示出中等质量水平，随之而来的是适度的相关偏见的可能性，使用纽卡斯尔-渥太华量表(NOS)，生存率（SR）在91％至100％之间。据报道，探查出血（BOP）的平均值为29.12％。边缘完整性在观察期显示出较高的成功率值，除了包括磨牙症患者的SR为31.60％。失败和/或断裂，主要是总量，需要更换，在三项研究中观察到。线性回归显示生存率与胶结类型及平均随访年限无统计学相关性(p=0.730ep=0.454)。研究间存在高度异质性(I2=93.74%,Q=79.672)。
结论：在本研究的范围内，整体氧化锆可能被认为是恢复单冠的可能选择，尤其是在后区。
方法：通过Medline/PubMed进行了广泛的电子搜索，Embase,和Cochrane图书馆数据库。对所收录文章的参考文献进行了其他手动搜索，以确定相关出版物。两名审阅者独立执行选择以及电子和手动搜索。
结果：从包括的九篇文章中，共有594名参与者和1657个单牙修复体，平均暴露时间为1.07年，随访期在0.3至2.1年之间。所有研究都显示出中等质量水平，随之而来的是适度的相关偏见的可能性，使用纽卡斯尔-渥太华量表(NOS)，生存率（SR）在91％至100％之间。据报道，探查出血（BOP）的平均值为29.12％。边缘完整性在观察期显示出较高的成功率值，除了包括磨牙症患者的SR为31.60％。失败和/或断裂，主要是总量，需要更换，在三项研究中观察到。线性回归显示生存率与胶结类型及平均随访年限无统计学相关性(p=0.730ep=0.454)。研究间存在高度异质性(I2=93.74%,Q=79.672)。
结论：在本研究的范围内，整体氧化锆可能被认为是恢复单冠的可能选择，尤其是在后区。
