PDF(Pubmed)
Abstract：
The quality control of essential oils (EO) principally aims at revealing the presence of adulterations and at quantifying compounds that are limited by law by evaluating EO chemical compositions, usually in terms of the normalised relative abundance of selected markers, for comparison to reference values reported in pharmacopoeias and/or international norms. Common adulterations of EO consist of the addition of cheaper EO or synthetic materials. This adulteration can be detected by calculating the percent normalised areas of selected markers or the enantiomeric composition of chiral components. The dilution of the EO with vegetable oils is another type of adulteration. This adulteration is quite devious, as it modifies neither the qualitative composition of the resulting EO nor the marker\'s normalised percentage abundance, which is no longer diagnostic, and an absolute quantitative analysis is required. This study aims at verifying the application of the two above approaches (i.e., normalised relative abundance and absolute quantitation) to detect EO adulterations, with examples involving selected commercial EO (lavender, bergamot and tea tree) adulterated with synthetic components, EO of different origin and lower economical values and heavy vegetable oils. The results show that absolute quantitation is necessary to highlight adulteration with heavy vegetable oils, providing that a reference quantitative profile is available.
摘要：
精油（EO）的质量控制主要旨在揭示掺假的存在，并通过评估EO化学成分来量化受法律限制的化合物。通常根据所选标记的归一化相对丰度，用于与药典和/或国际规范中报告的参考值进行比较。常见的EO掺杂包括添加更便宜的EO或合成材料。这种掺杂可以通过计算所选择的标记物的归一化面积百分比或手性组分的对映体组成来检测。用植物油稀释EO是另一种掺假。这种掺假是相当狡猾的，因为它既不修改所得EO的定性组成，也不修改标记的归一化丰度百分比，这不再是诊断，需要进行绝对的定量分析。本研究旨在验证上述两种方法的应用(即，归一化相对丰度和绝对定量)以检测EO掺杂，示例涉及选定的商业环氧乙烷(薰衣草，佛手和茶树）掺有合成成分，不同来源和较低经济价值的EO和重植物油。结果表明，绝对定量是必要的，以突出掺假与重植物油，提供参考定量概况。
