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Abstract：
OBJECTIVE: To compare outcomes of laser assisted deep sclerectomy (LADS) and conventional trabeculectomy both combined with phacoemulsification.
METHODS: We divided 36 eyes into 2 groups, one group with LADS and the other Trabeculectomy. Patients were measured post operatively at 1, 3, 6, 9 months, 1, 2, 3 years for intraocular pressure (IOP), best corrected visual acuity (BCVA) and number of medications.
RESULTS: In the trabeculectomy group, after 3 year follow up, IOP was 14.67 ± 3.14, 15.27 ± 4.28 and 17.00 ± 7.79, BCVA improved to 0.17 ± 0.18, 0.24 ± 0.20 and 0.24 ± 0.27 and number of medications reduced to 0.6 ± 0.6, 1.1 ± 1.2, and 1.5 ± 1.5. Complete success rate after 3 years was 100%, 80.0% & 80.0% and Qualified success rate was 100%, 88.9% & 88.9%. In the LADS group, after 3 years follow up, IOP was 14.11 ± 3.91, 16.07 ± 5.51, 15.80 ± 6.07, BCVA improved to 0.13 ± 0.11, 0.10 ± 0.15, 0.11 ± 0.13 and medications reduced to 1 ± 1.1, 1.5 ± 1.0 and 1.8 ± 1.0. Complete success after 3 years was 85.7%, 57.1% & 57.1% whereas qualified success was 92.3%, 84.6% & 84.6%.
CONCLUSIONS: Main limitations of our study were small sample size and lack of prospective comparison. However we were able to perfom the surgery comfortably due to the relatively shorter learning curve compared to conventional NPDS.
METHODS: We divided 36 eyes into 2 groups, one group with LADS and the other Trabeculectomy. Patients were measured post operatively at 1, 3, 6, 9 months, 1, 2, 3 years for intraocular pressure (IOP), best corrected visual acuity (BCVA) and number of medications.
RESULTS: In the trabeculectomy group, after 3 year follow up, IOP was 14.67 ± 3.14, 15.27 ± 4.28 and 17.00 ± 7.79, BCVA improved to 0.17 ± 0.18, 0.24 ± 0.20 and 0.24 ± 0.27 and number of medications reduced to 0.6 ± 0.6, 1.1 ± 1.2, and 1.5 ± 1.5. Complete success rate after 3 years was 100%, 80.0% & 80.0% and Qualified success rate was 100%, 88.9% & 88.9%. In the LADS group, after 3 years follow up, IOP was 14.11 ± 3.91, 16.07 ± 5.51, 15.80 ± 6.07, BCVA improved to 0.13 ± 0.11, 0.10 ± 0.15, 0.11 ± 0.13 and medications reduced to 1 ± 1.1, 1.5 ± 1.0 and 1.8 ± 1.0. Complete success after 3 years was 85.7%, 57.1% & 57.1% whereas qualified success was 92.3%, 84.6% & 84.6%.
CONCLUSIONS: Main limitations of our study were small sample size and lack of prospective comparison. However we were able to perfom the surgery comfortably due to the relatively shorter learning curve compared to conventional NPDS.
摘要：
■比较激光辅助深层巩膜切除术（LADS）和常规小梁切除术联合超声乳化手术的结果。
■我们把36只眼睛分成2组,一组进行LADS，另一组进行小梁切除术。术后1、3、6、9个月对患者进行测量,1、2、3年眼压（IOP），最佳矫正视力（BCVA）和药物数量。
■小梁切除术组，经过3年的随访，眼压分别为14.67±3.14、15.27±4.28和17.00±7.79，BCVA分别提高至0.17±0.18、0.24±0.20和0.24±0.27，用药次数分别减少至0.6±0.6、1.1±1.2和1.5±1.5。3年后的完全成功率为100%，80.0%和80.0%，成功率为100%，88.9%和88.9%。在LADS组中,经过3年的随访,眼压为14.11±3.91、16.07±5.51、15.80±6.07，BCVA改善至0.13±0.11、0.10±0.15、0.11±0.13，药物治疗降低至1±1.1、1.5±1.0和1.8±1.0。3年后的成功率为85.7%，57.1%和57.1%，合格成功率为92.3%，84.6%和84.6%。
■我们研究的主要局限性是样本量小和缺乏前瞻性比较。然而，由于与常规NPDS相比学习曲线相对较短，我们能够舒适地进行手术。
■我们把36只眼睛分成2组,一组进行LADS，另一组进行小梁切除术。术后1、3、6、9个月对患者进行测量,1、2、3年眼压（IOP），最佳矫正视力（BCVA）和药物数量。
■小梁切除术组，经过3年的随访，眼压分别为14.67±3.14、15.27±4.28和17.00±7.79，BCVA分别提高至0.17±0.18、0.24±0.20和0.24±0.27，用药次数分别减少至0.6±0.6、1.1±1.2和1.5±1.5。3年后的完全成功率为100%，80.0%和80.0%，成功率为100%，88.9%和88.9%。在LADS组中,经过3年的随访,眼压为14.11±3.91、16.07±5.51、15.80±6.07，BCVA改善至0.13±0.11、0.10±0.15、0.11±0.13，药物治疗降低至1±1.1、1.5±1.0和1.8±1.0。3年后的成功率为85.7%，57.1%和57.1%，合格成功率为92.3%，84.6%和84.6%。
■我们研究的主要局限性是样本量小和缺乏前瞻性比较。然而，由于与常规NPDS相比学习曲线相对较短，我们能够舒适地进行手术。
