METHODS: A self-report questionnaire that integrated the Spanish version of the Depression, Anxiety and Stress Scale-21 items (DASS-21) and the Perceived Stress Questionnaire (PSS) was designed to gather sociodemographic data and information related to the effects of lockdown on the lives of IBD patients. Twelve IBD units invited their patients to answer the anonymous online survey between the 1st July and the 25th August 2020.
RESULTS: Of the 693 survey participants with IBD, 67% were women and the mean age was 43 (SD 12). Sixty-one percent had ulcerative colitis, 36% Crohn\'s disease and 3% indeterminate colitis. DASS-21 scores indicate that during lockdown the estimated prevalence of depression was 11% [95% CI 8.2-13%], anxiety 20% [95% CI 17 to 23%] and stress 18% [95% CI 8.2-13%]. Multivariate analysis showed that the perceived high risk of COVID-19 infection because of having IBD and maladaptation to government measures to reduce the spread of disease doubled the risk of anxiety and stress during lockdown.
CONCLUSIONS: In the short-term, lockdown during the COVID-19 pandemic seemed to have an impact on the already affected mental health of our IBD patients in Spain.
方法:一份自我报告问卷,整合了西班牙语版的抑郁症,焦虑和压力量表-21项目(DASS-21)和感知压力问卷(PSS)旨在收集与封锁对IBD患者生活影响相关的社会人口统计学数据和信息。12个IBD单位邀请他们的患者在2020年7月1日至8月25日之间回答匿名在线调查。
结果:在693名IBD调查参与者中,67%为女性,平均年龄为43(SD12)。61%的人患有溃疡性结肠炎,36%的克罗恩病和3%的不确定结肠炎。DASS-21得分表明,在封锁期间,抑郁症的估计患病率为11%[95%CI8.2-13%],焦虑20%[95%CI17至23%]和压力18%[95%CI8.2-13%]。多变量分析显示,由于患有IBD和对政府减少疾病传播的措施不适应,认为COVID-19感染的高风险使封锁期间焦虑和压力的风险增加了一倍。
结论:在短期内,COVID-19大流行期间的封锁似乎对西班牙IBD患者已经受到影响的心理健康产生了影响。