Abstract：
This prospective, observational cohort study investigated the effects of multidisciplinary rehabilitation of post Covid-19 sequelae and persistent symptoms and their impact on patients\' functioning and quality of life.
From 58 patients referred for neurorehabilitation, 43 were eligible for and participated in the present study. Before and after 8 weeks of rehabilitation, patients underwent physical, neuropsychological and respiratory evaluations and assessment of functional independence, impact of fatigue and quality of life.
Forty of 43 individuals (52 ± 11.4 years, 24 male) completed the rehabilitation program. Fatigue (87.5%), dyspnea and/or shortness of breath (62.5%), and cognitive impairment (37.5%) were reported by both previously hospitalized and home-confined patients. Neurological sequelae (35.5%) were present only in hospitalized patients. After 8 weeks of rehabilitation, patients reported significant improvements in motor functional independence, upper and lower limb functionality, impact of fatigue on daily activities, respiratory muscle strength, cognitive performance, and quality of life.
Post Covid-19 patients present with heterogeneous neurological, physical, and respiratory impairments requiring a multidisciplinary rehabilitation approach to reduce disability and improve functionality and quality of life. A comprehensive assessment of clinical profiles and responses to rehabilitation may facilitate the identification of rehabilitation candidates and help to design effective rehabilitation interventions.Implication for rehabilitationPost Covid-19 patients present multiple, heterogeneous neurological, physical and respiratory impairments that are observed in both previously hospitalized and home-confined patients.Eight weeks of multidisciplinary rehabilitation may significantly reduce disability and improve functionality and quality of life.A comprehensive assessment of their clinical profile and response to rehabilitation may facilitate the identification of rehabilitation candidates and help to design more effective rehabilitation interventions.
From 58 patients referred for neurorehabilitation, 43 were eligible for and participated in the present study. Before and after 8 weeks of rehabilitation, patients underwent physical, neuropsychological and respiratory evaluations and assessment of functional independence, impact of fatigue and quality of life.
Forty of 43 individuals (52 ± 11.4 years, 24 male) completed the rehabilitation program. Fatigue (87.5%), dyspnea and/or shortness of breath (62.5%), and cognitive impairment (37.5%) were reported by both previously hospitalized and home-confined patients. Neurological sequelae (35.5%) were present only in hospitalized patients. After 8 weeks of rehabilitation, patients reported significant improvements in motor functional independence, upper and lower limb functionality, impact of fatigue on daily activities, respiratory muscle strength, cognitive performance, and quality of life.
Post Covid-19 patients present with heterogeneous neurological, physical, and respiratory impairments requiring a multidisciplinary rehabilitation approach to reduce disability and improve functionality and quality of life. A comprehensive assessment of clinical profiles and responses to rehabilitation may facilitate the identification of rehabilitation candidates and help to design effective rehabilitation interventions.Implication for rehabilitationPost Covid-19 patients present multiple, heterogeneous neurological, physical and respiratory impairments that are observed in both previously hospitalized and home-confined patients.Eight weeks of multidisciplinary rehabilitation may significantly reduce disability and improve functionality and quality of life.A comprehensive assessment of their clinical profile and response to rehabilitation may facilitate the identification of rehabilitation candidates and help to design more effective rehabilitation interventions.
摘要：
这个未来,观察性队列研究调查了Covid-19后遗症和持续性症状的多学科康复的效果及其对患者功能和生活质量的影响。
从58名接受神经康复的患者中，43人符合资格并参与了本研究。复健前后8周,患者接受了体检，神经心理学和呼吸评估以及功能独立性的评估，疲劳和生活质量的影响。
43人中有40人（52±11.4岁，24名男性）完成了康复计划。疲劳(87.5%),呼吸困难和/或呼吸急促（62.5%），和认知障碍(37.5%)的报告均为既往住院和家庭住院患者.仅在住院患者中出现神经系统后遗症（35.5％）。经过8周的康复，患者报告运动功能独立性显著改善，上肢和下肢功能，疲劳对日常活动的影响，呼吸肌力量,认知表现，和生活质量。
Covid-19后出现神经异质性的患者，物理，和呼吸损伤需要多学科康复方法，以减少残疾，提高功能和生活质量。对临床概况和康复反应的全面评估可能有助于识别康复候选人，并有助于设计有效的康复干预措施。对康复的影响Covid-19后患者表现出多种，异质性神经学，在先前住院和家庭住院患者中观察到的身体和呼吸损伤。八周的多学科康复可以显着减少残疾并改善功能和生活质量。全面评估其临床概况和对康复的反应可能有助于识别康复候选人，并有助于设计更有效的康复干预措施。
从58名接受神经康复的患者中，43人符合资格并参与了本研究。复健前后8周,患者接受了体检，神经心理学和呼吸评估以及功能独立性的评估，疲劳和生活质量的影响。
43人中有40人（52±11.4岁，24名男性）完成了康复计划。疲劳(87.5%),呼吸困难和/或呼吸急促（62.5%），和认知障碍(37.5%)的报告均为既往住院和家庭住院患者.仅在住院患者中出现神经系统后遗症（35.5％）。经过8周的康复，患者报告运动功能独立性显著改善，上肢和下肢功能，疲劳对日常活动的影响，呼吸肌力量,认知表现，和生活质量。
Covid-19后出现神经异质性的患者，物理，和呼吸损伤需要多学科康复方法，以减少残疾，提高功能和生活质量。对临床概况和康复反应的全面评估可能有助于识别康复候选人，并有助于设计有效的康复干预措施。对康复的影响Covid-19后患者表现出多种，异质性神经学，在先前住院和家庭住院患者中观察到的身体和呼吸损伤。八周的多学科康复可以显着减少残疾并改善功能和生活质量。全面评估其临床概况和对康复的反应可能有助于识别康复候选人，并有助于设计更有效的康复干预措施。
