关键词: palliative radiation therapy priapism prostate cancer radiotherapy volumetric modulated arc therapy

来  源:   DOI:10.7759/cureus.17287   PDF(Pubmed)

Abstract:
Malignant priapism is a condition of painful induration and erection of the penis secondary to metastatic infiltration by a neoplasm. This condition is associated with a poor prognosis. We report on a case of an 87-year-old man who presented with a painful, partially erected penis subsequent to a diagnosis of metastatic Gleason 4+5 prostate cancer. Magnetic resonance imaging (MRI) showed diffuse bilateral infiltration of his corpora cavernosa. The core biopsy of the penile nodule revealed it to be a poorly differentiated carcinoma consistent with prostatic origin. The patient\'s symptoms were completely resolved after treatment with high-dose palliative conformal radiotherapy (40Gy in 16 fractions). We systemically reviewed clinical reports of palliative radiotherapy for malignant priapism with the aim to gain more information on the management of this rare condition.
摘要:
恶性阴茎异常勃起是由肿瘤转移浸润继发的疼痛性硬结和阴茎勃起的病症。这种情况与不良预后有关。我们报道了一个87岁的男人,在诊断为转移性Gleason4+5前列腺癌后,阴茎部分竖立。磁共振成像(MRI)显示他的海绵体弥漫性双侧浸润。阴茎结节的核心活检显示它是与前列腺起源一致的低分化癌。大剂量姑息适形放疗(16分40Gy)治疗后,患者症状完全缓解。我们系统地审查了姑息性放疗治疗恶性阴茎异常勃起的临床报告,目的是获得有关这种罕见疾病治疗的更多信息。
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