UNASSIGNED: Information on updated etiology, clinical symptoms, diagnosis, and treatment of rpc has been obtained via extensive research of electronic literature published between 1976 and 2019 using PubMed and medline databases. English was the language of use. Search inputs included \'relapsing polychondritis,\' \'polychondritis,\' \'relapsing polychondritis symptoms,\' and \'treatment of relapsing polychondritis.\' Published articles in English that outlined and reported rpc\'s clinical manifestations and treatment ultimately met the inclusion criteria. Articles that failed to report the above and reported on other cartilaginous diseases met the exclusion criteria.
UNASSIGNED: Utilizing an extensive overview of work undertaken in critical areas of RPC research, this review intends to further explore and educate the approach to this disease in all dimensions from pathophysiology, diagnosis, and management.
UNASSIGNED: RPC is a rare multi-systemic autoimmune disease and possibly fatal. The management remains empiric and is identified based on the severity of the disease per case. The optimal way to advance is to continue sharing data on RPC from reference centers; furthermore, clinical trials in randomized control groups must provide evidence-based treatment and management. Acquiring such information will refine the current knowledge of RPC, which will improve not only treatment but also diagnostic methods, including imaging and biological markers.
■有关最新病因的信息,临床症状,诊断,rpc的治疗是通过使用PubMed和medline数据库对1976年至2019年之间发表的电子文献进行的广泛研究获得的。英语是使用的语言。搜索输入包括复发性多软骨炎,\'\'多软骨炎,\'\'复发性多软骨炎症状,复发性多软骨炎的治疗。以英文发表的文章概述并报告了rpc的临床表现和治疗最终符合纳入标准。未能报告上述内容并报告其他软骨疾病的文章符合排除标准。
■利用在RPC研究的关键领域开展的工作的广泛概述,这篇综述旨在从病理生理学的各个方面进一步探索和教育这种疾病的方法,诊断,和管理。
■RPC是一种罕见的多系统自身免疫性疾病,可能致命。管理仍然是经验性的,并根据每例疾病的严重程度进行识别。推进的最佳方式是继续从参考中心共享RPC上的数据;此外,随机对照组的临床试验必须提供循证治疗和管理.获取这些信息将完善RPC的当前知识,这不仅会改善治疗,还会改善诊断方法,包括成像和生物标记。