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Abstract：
The antimicrobial peptide database (APD) has served the antimicrobial peptide field for 18 years. Because it is widely used in research and education, this article documents database milestones and key events that have transformed it into the current form. A comparison is made for the APD peptide statistics between 2010 and 2020, validating the major database findings to date. We also describe new additions ranging from peptide entries to search functions. Of note, the APD also contains antimicrobial peptides from host microbiota, which are important in shaping immune systems and could be linked to a variety of human diseases. Finally, the database has been re-programmed to the web branding and latest security compliance of the University of Nebraska Medical Center. The reprogrammed APD can be accessed at https://aps.unmc.edu.
摘要：
抗菌肽数据库（APD）已经为抗菌肽领域服务了18年。因为它广泛用于研究和教育，本文记录了数据库里程碑和关键事件，这些事件已将其转换为当前形式。对2010年和2020年之间的APD肽统计进行了比较，验证了迄今为止的主要数据库发现。我们还描述了从肽条目到搜索功能的新添加。值得注意的是，APD还含有来自宿主微生物群的抗菌肽，这对塑造免疫系统很重要，可能与各种人类疾病有关。最后,该数据库已被重新编程为内布拉斯加州大学医学中心的网络品牌和最新的安全合规性。重新编程的APD可以在https://aps访问。unmc.edu.
