PDF(Pubmed)
Abstract：
Invasive fungal infections are being increasingly identified recently. Scedosporium is a significant cause of non-Aspergillus mold infection. It can cause disseminated disease in an immunocompromised host and localized pulmonary infection in immunocompetent ones, especially in those with preformed lung cavities. We present a case of scedosporiosis in an elderly female with bronchiectasis who presented with refractory pulmonary symptoms and infiltrates. The case emphasizes the need to keep the fungal infection in the differential diagnosis of refractory infiltrates in immunocompetent individuals without preformed cavities if they have bronchiectasis. Voriconazole monotherapy can be used as the first-line in proven cases of scedosporiosis.
摘要：
侵袭性真菌感染最近越来越多地被发现。Scedosporium是非曲霉霉菌感染的重要原因。它可以在免疫功能低下的宿主中引起播散性疾病，在免疫功能低下的宿主中引起局部肺部感染，尤其是那些有预制肺腔的人。我们介绍了一名患有支气管扩张症的老年女性的scedosporiosis病例，该病例表现为难治性肺部症状和浸润。该病例强调，如果有支气管扩张，则在没有预先形成的空洞的免疫活性个体的难治性浸润的鉴别诊断中，需要保持真菌感染。伏立康唑单一疗法可用作已证实的scedosporiosis病例的一线治疗。
