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Abstract：
AMIS: Alcohol consumption has multiple negative consequences for people with epilepsy, including precipitation of seizure or status epilepticus, worsening of seizure control, increased adverse effects of anti-seizure medications, increased sudden unexpected death in epilepsy, and premature mortality. The aim of this study was to investigate alcohol use and explore the sociodemographic and clinical factors associated with alcohol use among patients with epilepsy in western China.
METHODS: A face-to-face questionnaire on alcohol use was conducted at Sichuan Provincial People\'s Hospital from December 2020 to June 2021. All adult patients who came to our epilepsy center (inpatient and outpatient) were invited to participate in this study. Logistic regression was used to evaluate the possible risk factors associated with alcohol use within the last 12 months.
RESULTS: A total of 425 patients completed this study, 24.2% of patients with epilepsy had used alcohol within the last 12 months, being male and having a history of alcohol use were independently associated factors. Among patients who had used alcohol within the last 12 months, 52.4% complained of worsening of seizure control, heavy alcohol use, and frequent alcohol use were independently associated with worsening of seizure control after alcohol use in patients with epilepsy.
CONCLUSIONS: This study revealed that the rate of alcohol use among patients with epilepsy was high. Male patients with a history of alcohol use were more prone to alcohol use after a diagnosis of epilepsy. Heavy alcohol use and frequent alcohol use were independently associated with worsening of seizure control after alcohol use in patients with epilepsy. Patient education on the destructive effects of alcohol use is needed for patients with epilepsy.
METHODS: A face-to-face questionnaire on alcohol use was conducted at Sichuan Provincial People\'s Hospital from December 2020 to June 2021. All adult patients who came to our epilepsy center (inpatient and outpatient) were invited to participate in this study. Logistic regression was used to evaluate the possible risk factors associated with alcohol use within the last 12 months.
RESULTS: A total of 425 patients completed this study, 24.2% of patients with epilepsy had used alcohol within the last 12 months, being male and having a history of alcohol use were independently associated factors. Among patients who had used alcohol within the last 12 months, 52.4% complained of worsening of seizure control, heavy alcohol use, and frequent alcohol use were independently associated with worsening of seizure control after alcohol use in patients with epilepsy.
CONCLUSIONS: This study revealed that the rate of alcohol use among patients with epilepsy was high. Male patients with a history of alcohol use were more prone to alcohol use after a diagnosis of epilepsy. Heavy alcohol use and frequent alcohol use were independently associated with worsening of seizure control after alcohol use in patients with epilepsy. Patient education on the destructive effects of alcohol use is needed for patients with epilepsy.
摘要：
饮酒对癫痫患者有多种负面影响，包括癫痫发作或癫痫持续状态的沉淀，癫痫发作控制恶化，抗癫痫药物的不良反应增加，癫痫突然意外死亡增加，过早死亡。这项研究的目的是调查中国西部癫痫患者的酒精使用情况，并探讨与酒精使用相关的社会人口统计学和临床因素。
方法：于2020年12月至2021年6月在四川省人民医院进行面对面的饮酒问卷调查。邀请所有来我们癫痫中心（住院和门诊）的成年患者参加本研究。采用Logistic回归分析评估过去12个月内与饮酒相关的可能危险因素。
结果：共有425名患者完成了这项研究，24.2%的癫痫患者在过去12个月内使用过酒精，男性和有饮酒史是独立的相关因素.在过去12个月内饮酒的患者中，52.4%抱怨癫痫发作控制恶化，大量饮酒，和频繁饮酒与癫痫患者饮酒后癫痫发作控制恶化独立相关。
结论：这项研究显示，癫痫患者的酒精使用率很高。有饮酒史的男性患者在诊断为癫痫后更容易饮酒。重度饮酒和频繁饮酒与癫痫患者饮酒后癫痫发作控制恶化独立相关。癫痫患者需要对患者进行有关饮酒破坏性影响的教育。
方法：于2020年12月至2021年6月在四川省人民医院进行面对面的饮酒问卷调查。邀请所有来我们癫痫中心（住院和门诊）的成年患者参加本研究。采用Logistic回归分析评估过去12个月内与饮酒相关的可能危险因素。
结果：共有425名患者完成了这项研究，24.2%的癫痫患者在过去12个月内使用过酒精，男性和有饮酒史是独立的相关因素.在过去12个月内饮酒的患者中，52.4%抱怨癫痫发作控制恶化，大量饮酒，和频繁饮酒与癫痫患者饮酒后癫痫发作控制恶化独立相关。
结论：这项研究显示，癫痫患者的酒精使用率很高。有饮酒史的男性患者在诊断为癫痫后更容易饮酒。重度饮酒和频繁饮酒与癫痫患者饮酒后癫痫发作控制恶化独立相关。癫痫患者需要对患者进行有关饮酒破坏性影响的教育。
