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Abstract：
To evaluate the influence of the result of a rapid streptococcal antigen test in paediatric pharyngotonsillitis infections, in terms of improvement of antibiotic therapy adherence.
Randomized community clinical trial with two study groups.
Primary Care Centers in Central Catalonia.
Patients aged from 3 to 15 years, who were attended at paediatric consultations on suspicion of pharyngotonsillitis caused by an infection between November 2010 and February 2011 (both included), were included in the study on a consecutive basis. 557 patients met the inclusion criteria and 519 were evaluated.
The control group received the usual diagnostic-therapeutic algorithm. Rapid streptococcal antigen test was additionally performed to experimental group participants and it was indicated the more convenient treatment.
Antibiotic adherence, non-adherence causes and socio-demographic risk factors were evaluated via telephone survey.
Antibiotics were prescribed to 65.6% and paediatricians of the control group were more likely to prescribe antibiotic than the ones in the intervention group (88.5% vs 45.5%, p< 0.0001). 64.8% followed doctor\'s treatment orders, being failure following medication scheduling the main cause of non-adherence (25.6%). Medication adherence was higher in the experimental group (68%) than in the control group (62.9%) but no significant differences were found.
Rapid strep test, complementing the use of Centor Criteria avoids unnecessary antibiotics prescriptions, but had not been proven to be effective in increasing medication adherence.
Randomized community clinical trial with two study groups.
Primary Care Centers in Central Catalonia.
Patients aged from 3 to 15 years, who were attended at paediatric consultations on suspicion of pharyngotonsillitis caused by an infection between November 2010 and February 2011 (both included), were included in the study on a consecutive basis. 557 patients met the inclusion criteria and 519 were evaluated.
The control group received the usual diagnostic-therapeutic algorithm. Rapid streptococcal antigen test was additionally performed to experimental group participants and it was indicated the more convenient treatment.
Antibiotic adherence, non-adherence causes and socio-demographic risk factors were evaluated via telephone survey.
Antibiotics were prescribed to 65.6% and paediatricians of the control group were more likely to prescribe antibiotic than the ones in the intervention group (88.5% vs 45.5%, p< 0.0001). 64.8% followed doctor\'s treatment orders, being failure following medication scheduling the main cause of non-adherence (25.6%). Medication adherence was higher in the experimental group (68%) than in the control group (62.9%) but no significant differences were found.
Rapid strep test, complementing the use of Centor Criteria avoids unnecessary antibiotics prescriptions, but had not been proven to be effective in increasing medication adherence.
摘要：
为了评估快速链球菌抗原测试结果对小儿咽喉炎感染的影响，在改善抗生素治疗依从性方面。
两个研究组的随机社区临床试验。
加泰罗尼亚中部的初级保健中心。
3至15岁的患者，在2010年11月至2011年2月期间，他们因涉嫌感染引起的咽喉炎而接受儿科咨询（均包括在内），被连续纳入研究。557例患者符合纳入标准，519例患者接受评估。
对照组接受常规的诊断-治疗算法。对实验组参与者进行了快速链球菌抗原测试，表明治疗更方便。
抗生素依从性，非依从性原因和社会人口统计学危险因素通过电话调查进行评估.
开抗生素的比例为65.6％，对照组的儿科医生比干预组的儿科医生更有可能开抗生素（88.5％vs45.5％，p<0.0001)。64.8%遵循医生的治疗命令，服药后失败是不依从的主要原因(25.6%)。实验组的药物依从性（68％）高于对照组（62.9％），但没有发现显着差异。
快速链球菌试验，补充使用Centor标准避免了不必要的抗生素处方，但尚未被证明对提高药物依从性有效。
两个研究组的随机社区临床试验。
加泰罗尼亚中部的初级保健中心。
3至15岁的患者，在2010年11月至2011年2月期间，他们因涉嫌感染引起的咽喉炎而接受儿科咨询（均包括在内），被连续纳入研究。557例患者符合纳入标准，519例患者接受评估。
对照组接受常规的诊断-治疗算法。对实验组参与者进行了快速链球菌抗原测试，表明治疗更方便。
抗生素依从性，非依从性原因和社会人口统计学危险因素通过电话调查进行评估.
开抗生素的比例为65.6％，对照组的儿科医生比干预组的儿科医生更有可能开抗生素（88.5％vs45.5％，p<0.0001)。64.8%遵循医生的治疗命令，服药后失败是不依从的主要原因(25.6%)。实验组的药物依从性（68％）高于对照组（62.9％），但没有发现显着差异。
快速链球菌试验，补充使用Centor标准避免了不必要的抗生素处方，但尚未被证明对提高药物依从性有效。
