PDF(Pubmed)
Abstract：
The thermal grill illusion (TGI) is a paradoxical perception of burning heat and pain resulting from the simultaneous application of interlaced warm and cold stimuli to the skin. The TGI is considered a type of chronic centralized pain and has been used to apply nociceptive stimuli without inflicting harm to human participants in the study of pain mechanisms. In addition, the TGI is an interesting phenomenon for researchers, and various topics related to the TGI have been investigated in several studies, which we will review here. According to previous studies, the TGI is generated by supraspinal interactions. To evoke the TGI, cold and warm cutaneous stimuli should be applied within the same dermatome or across dermatomes corresponding to adjacent spinal segments, and a significant difference between cold and warm temperatures is necessary. In addition, due the presence of chronic pain, genetic factors, and sexual differences, the intensity of the TGI can differ. In addition, cold noxious stimulation, topical capsaicin, analgesics, self-touch, and the presence of psychological diseases can decrease the intensity of the TGI. Because the TGI corresponds to chronic centralized pain, we believe that the findings of previous studies can be applied to future studies to identify chronic pain mechanisms and clinical practice for pain management.
摘要：
热格栅错觉（TGI）是对皮肤同时施加交错的温暖和寒冷刺激而引起的灼热和疼痛的矛盾感知。TGI被认为是一种慢性集中式疼痛，已用于施加伤害性刺激，而不会对疼痛机制研究中的人类参与者造成伤害。此外,TGI对研究人员来说是一个有趣的现象，与TGI相关的各种主题已经在几项研究中进行了调查，我们将在这里回顾。根据以前的研究,TGI是由脊柱上相互作用产生的。为了唤起TGI，冷和温暖的皮肤刺激应应用于同一皮刀内或对应于相邻脊柱节段的皮刀内，并且在寒冷和温暖的温度之间的显着差异是必要的。此外,由于慢性疼痛的存在，遗传因素,和性别差异，TGI的强度可以不同。此外,寒冷的有害刺激，局部辣椒素，镇痛药,自我触摸,心理疾病的存在可以降低TGI的强度。因为TGI对应于慢性集中式疼痛，我们相信以前的研究结果可以应用于未来的研究,以确定慢性疼痛机制和疼痛管理的临床实践.
