关键词: COVID-19 Cepheid XpertXpress SARS-CoV-2 SARS-CoV-2 diagnostic testing single nucleotide polymorphisms

Mesh : COVID-19 / epidemiology virology Cities / epidemiology Coronavirus Nucleocapsid Proteins / genetics Databases, Genetic Genome, Viral Humans Mutation Phosphoproteins / genetics SARS-CoV-2 / genetics United States / epidemiology

来  源:   DOI:10.1016/j.diagmicrobio.2021.115468   PDF(Sci-hub)   PDF(Pubmed)

Abstract:
Nasal and nasopharyngeal swab specimens tested by the Cepheid Xpert Xpress SARS-CoV-2 were analyzed by whole-genome sequencing based on impaired detection of the N2 target. Each viral genome had at least one mutation in the N gene, which likely arose independently in the New York City and Pittsburgh study sites.
摘要:
通过造父变星XpertXpressSARS-CoV-2测试的鼻和鼻咽拭子标本通过基于N2靶标受损检测的全基因组测序进行分析。每个病毒基因组在N基因中至少有一个突变,这可能是在纽约市和匹兹堡研究地点独立出现的。
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