关键词: Hyaluronic acid filler delayed inflammatory reaction filler reaction

Mesh : Adult Colchicine / adverse effects Cosmetic Techniques / adverse effects Dermal Fillers / adverse effects Female Humans Hyaluronic Acid / adverse effects Hyaluronoglucosaminidase Vaccination

来  源:   DOI:10.1080/14764172.2021.1967997

Abstract:
Delayed inflammatory reactions (DIRs) associated with hyaluronic acid injections are not rare and can be seen in up to 4.25% of patients. Although the exact mechanism is not clear, several triggering factors, including infections, trauma, and dental procedures, were reported in the literature. A 43-year-old female patient treated with HA fillers developed an inflammatory reaction following vaccination in all areas of injection, including temples, lips, and lower eyelids. Systemic steroid and ciprofloxacin were used as a first-line treatment without response. Colchicine 1 mg/day along with hyaluronidase in lower eyelids improved all lesions successfully.
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