PDF(Pubmed)
Abstract：
UNASSIGNED: Cerebral palsy is the most frequent motor disability in childhood and is associated with a higher incidence of seizure disorders. In many instances, it is recognized that motor difficulties, as well as seizures, are from the same underlying brain lesion. However, self-limited childhood epilepsies, being a common group of epilepsy syndromes, would be expected to occur in patients with cerebral palsy merely on chance association and be unrelated to the structural brain imaging abnormality causing the motor impairment. Differential diagnosis in this case is important determining the long-term prognosis and need for anticonvulsant treatment.
UNASSIGNED: Here, we report two patients with cerebral palsy combined with epilepsy, whose age at onset, seizure semiology and electroclinical features were similar to children with self-limited childhood-specific seizure disorders (childhood epilepsy with centrotemporal spikes and Panayiotopoulos syndrome).
UNASSIGNED: These cases highlight the importance of comprehensive differential diagnosis of seizures in cerebral palsy. Co-existence of age-dependent focal epilepsies with an underlying brain pathology as white matter injury, not affecting the cerebral cortex, might take place in the case of children with impaired motor skills. With health systems increasingly utilizing clinical pathways, it is important to consider the possibility of a self-limited childhood epilepsy and avoid aggressive and unnecessary medication treatment in children with cerebral palsy.
UNASSIGNED: Here, we report two patients with cerebral palsy combined with epilepsy, whose age at onset, seizure semiology and electroclinical features were similar to children with self-limited childhood-specific seizure disorders (childhood epilepsy with centrotemporal spikes and Panayiotopoulos syndrome).
UNASSIGNED: These cases highlight the importance of comprehensive differential diagnosis of seizures in cerebral palsy. Co-existence of age-dependent focal epilepsies with an underlying brain pathology as white matter injury, not affecting the cerebral cortex, might take place in the case of children with impaired motor skills. With health systems increasingly utilizing clinical pathways, it is important to consider the possibility of a self-limited childhood epilepsy and avoid aggressive and unnecessary medication treatment in children with cerebral palsy.
摘要：
脑性瘫痪是儿童时期最常见的运动障碍，并且与癫痫发作有关。在许多情况下,人们认识到，电机困难，以及癫痫发作，来自相同的潜在脑部病变。然而,自我限制的儿童癫痫，作为一组常见的癫痫综合征，预计仅在偶然性关联的脑瘫患者中发生，并且与导致运动障碍的结构性脑影像学异常无关。在这种情况下，鉴别诊断对于确定长期预后和抗惊厥治疗的需要很重要。
■这里，我们报告了两名脑瘫合并癫痫患者，其发病年龄，癫痫发作的符号学和临床电特征与患有自限性儿童特异性癫痫发作障碍(伴有中央颞区尖峰和Panayiotopoulos综合征的儿童癫痫)的儿童相似.
■这些病例突出了对脑瘫癫痫发作进行综合鉴别诊断的重要性。年龄依赖性局灶性癫痫与脑白质损伤的潜在病理共存，不会影响大脑皮层，可能发生在运动技能受损的儿童的情况下。随着卫生系统越来越多地利用临床路径，重要的是要考虑儿童自限性癫痫的可能性,并避免对脑瘫儿童进行积极和不必要的药物治疗.
■这里，我们报告了两名脑瘫合并癫痫患者，其发病年龄，癫痫发作的符号学和临床电特征与患有自限性儿童特异性癫痫发作障碍(伴有中央颞区尖峰和Panayiotopoulos综合征的儿童癫痫)的儿童相似.
■这些病例突出了对脑瘫癫痫发作进行综合鉴别诊断的重要性。年龄依赖性局灶性癫痫与脑白质损伤的潜在病理共存，不会影响大脑皮层，可能发生在运动技能受损的儿童的情况下。随着卫生系统越来越多地利用临床路径，重要的是要考虑儿童自限性癫痫的可能性,并避免对脑瘫儿童进行积极和不必要的药物治疗.
