Abstract：
Cancer is a major health problem worldwide and the second leading cause of death following cardiovascular diseases. Breast cancer is the leading cause of mortality and morbidity among women and one of the most common malignant neoplasms prompt to metastatic disease. In the present review, the mechanisms of the major cell adhesion molecules involved in tumor invasion are discussed, focusing on the case of breast cancer. A non-systematic updated revision of the literature was performed in order to assemble information regarding the expression of the adhesion cell molecules associated with metastasis.
摘要：
癌症是全球范围内的主要健康问题，是仅次于心血管疾病的第二大死亡原因。乳腺癌是女性死亡和发病的主要原因，也是导致转移性疾病的最常见恶性肿瘤之一。在本次审查中，讨论了参与肿瘤侵袭的主要细胞粘附分子的机制，关注乳腺癌的情况。对文献进行了非系统的更新修订，以收集有关与转移相关的粘附细胞分子表达的信息。
