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Abstract：
UNASSIGNED: To carry out a systematic review of the effect of cardiac rehabilitation (CR) and its components on cardiovascular outcomes in patients with stable angina.
UNASSIGNED: We searched the databases including Ovid MEDLINE, Ovid Embase, Scopus, Web of Science, Google Scholar, and EBSCO CINAHL from their inception up to November 1, 2017. The search was not restricted to time or publication status but was limited to the English language. Two independent investigators screened the identified studies and extracted the data in duplicate. We reviewed the included studies and, where possible, pooled their results and conducted meta-analyses. Risk of bias was assessed using Cochrane Collaboration tools.
UNASSIGNED: The search identified 7508 studies. Ten randomized trials including 4005 participants with the mean (SD) age of 59.6 (5.7) years were considered eligible for inclusion in our analyses. The results of meta-analyses of exercise-based CR for patients with stable angina revealed that CR improved exercise capacity (the difference between baseline and follow-up was 0.76 watt [0.49 to 1.02] higher in the CR group vs the non-CR group) and decreased angina frequency (standard mean difference, -0.27 [CI, -0.43 to 0.11]). No significant differences were noted in other outcomes, including quality of life. Mortality could not be adequately assessed because it was analyzed in only 1 exercise-based CR study.
UNASSIGNED: Our systematic review, involving a relatively small number of studies with low to moderate risk of bias and with considerable heterogeneity, found a significant decrease in angina frequency and increase in exercise capacity in patients with stable angina who participated in an exercise-based CR program. Studies involving the impact of components of CR are limited and generally report beneficial outcomes. Additional studies are needed to clarify the possible role of CR in the management of patients with stable angina.
UNASSIGNED: We searched the databases including Ovid MEDLINE, Ovid Embase, Scopus, Web of Science, Google Scholar, and EBSCO CINAHL from their inception up to November 1, 2017. The search was not restricted to time or publication status but was limited to the English language. Two independent investigators screened the identified studies and extracted the data in duplicate. We reviewed the included studies and, where possible, pooled their results and conducted meta-analyses. Risk of bias was assessed using Cochrane Collaboration tools.
UNASSIGNED: The search identified 7508 studies. Ten randomized trials including 4005 participants with the mean (SD) age of 59.6 (5.7) years were considered eligible for inclusion in our analyses. The results of meta-analyses of exercise-based CR for patients with stable angina revealed that CR improved exercise capacity (the difference between baseline and follow-up was 0.76 watt [0.49 to 1.02] higher in the CR group vs the non-CR group) and decreased angina frequency (standard mean difference, -0.27 [CI, -0.43 to 0.11]). No significant differences were noted in other outcomes, including quality of life. Mortality could not be adequately assessed because it was analyzed in only 1 exercise-based CR study.
UNASSIGNED: Our systematic review, involving a relatively small number of studies with low to moderate risk of bias and with considerable heterogeneity, found a significant decrease in angina frequency and increase in exercise capacity in patients with stable angina who participated in an exercise-based CR program. Studies involving the impact of components of CR are limited and generally report beneficial outcomes. Additional studies are needed to clarify the possible role of CR in the management of patients with stable angina.
摘要：
■对心脏康复（CR）及其组成部分对稳定型心绞痛患者心血管结局的影响进行系统评价。
■我们搜索了包括OvidMEDLINE在内的数据库，OvidEmbase,Scopus,WebofScience,谷歌学者，和EBSCOCINAHL从成立到2017年11月1日。搜索不限于时间或出版物状态，但仅限于英语。两名独立研究人员筛选了确定的研究，并一式两份地提取了数据。我们回顾了纳入的研究，在可能的情况下,汇集他们的结果并进行荟萃分析.使用Cochrane协作工具评估偏倚风险。
■搜索确定了7508项研究。包括4005名平均（SD）年龄为59.6（5.7）岁的参与者在内的10项随机试验被认为有资格纳入我们的分析。对稳定型心绞痛患者进行基于运动的CR的荟萃分析结果表明，CR改善了运动能力（CR组与非CR组相比，基线和随访之间的差异高0.76瓦[0.49至1.02]）并降低了心绞痛频率（标准平均差，-0.27[CI，-0.43至0.11]）。在其他结果中没有发现显著差异，包括生活质量。死亡率无法充分评估，因为仅在1项基于运动的CR研究中对其进行了分析。
■我们的系统评价，涉及相对少量的研究，这些研究具有低到中等的偏倚风险和相当大的异质性，发现参加基于运动的CR计划的稳定型心绞痛患者的心绞痛频率显着降低，运动能力增加。涉及CR成分影响的研究是有限的，通常报告有益的结果。需要进一步的研究来阐明CR在治疗稳定型心绞痛患者中的可能作用。
■我们搜索了包括OvidMEDLINE在内的数据库，OvidEmbase,Scopus,WebofScience,谷歌学者，和EBSCOCINAHL从成立到2017年11月1日。搜索不限于时间或出版物状态，但仅限于英语。两名独立研究人员筛选了确定的研究，并一式两份地提取了数据。我们回顾了纳入的研究，在可能的情况下,汇集他们的结果并进行荟萃分析.使用Cochrane协作工具评估偏倚风险。
■搜索确定了7508项研究。包括4005名平均（SD）年龄为59.6（5.7）岁的参与者在内的10项随机试验被认为有资格纳入我们的分析。对稳定型心绞痛患者进行基于运动的CR的荟萃分析结果表明，CR改善了运动能力（CR组与非CR组相比，基线和随访之间的差异高0.76瓦[0.49至1.02]）并降低了心绞痛频率（标准平均差，-0.27[CI，-0.43至0.11]）。在其他结果中没有发现显著差异，包括生活质量。死亡率无法充分评估，因为仅在1项基于运动的CR研究中对其进行了分析。
■我们的系统评价，涉及相对少量的研究，这些研究具有低到中等的偏倚风险和相当大的异质性，发现参加基于运动的CR计划的稳定型心绞痛患者的心绞痛频率显着降低，运动能力增加。涉及CR成分影响的研究是有限的，通常报告有益的结果。需要进一步的研究来阐明CR在治疗稳定型心绞痛患者中的可能作用。
