关键词: biologic drugs biologics immunology mast cell activation syndrome mastocytosis

来  源:   DOI:10.1111/ajd.13674   PDF(Sci-hub)

Abstract:
Treatment for telangiectasia macularis eruptiva perstans (TMEP) is often challenging due to lack of an established first-line therapy and as such is primarily focused on symptomatic relief. Omalizumab shows promise as a potential therapy for mast cell disorders; however, its efficacy in TMEP is yet to be established. This case describes a 72-year-old woman with chronic refractory TMEP achieving symptomatic remission within 4 months of commencing omalizumab therapy.
摘要:
由于缺乏既定的一线治疗,黄斑毛细血管扩张症(TMEP)的治疗通常具有挑战性,因此主要集中在症状缓解上。奥马珠单抗显示出有望作为肥大细胞疾病的潜在疗法;然而,其在TMEP中的疗效尚待确定。该病例描述了一名72岁女性,患有慢性难治性TMEP,在开始奥马珠单抗治疗4个月内达到症状缓解。
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