This was a case control study. We included 110 children attending the Pediatric ophthalmology outpatient department of a tertiary eye care center in South India between September 2019 and June 2020. Fifty-five children with VKC and 55 normal age and gender-matched children were examined by Sirius tomographer/topographer (CSO, Italy) to determine the PCE, thinnest corneal thickness (TCT), simulated K (Sim K), keratoconus front (KVf) and keratoconus vertex back (KVb). The parameters were compared between the two groups.
A total of 220 eyes of 110 children were examined. The mean age in both groups was 10.44 ± 3.28 years, each group included 44 males and 11 females. There was no statistically significant difference in TCT and Sim K between the two groups. The mean PCE was 18.8 ± 8.4 μm in VKC group and 11.7 ± 3.9 μm in control group (P < 0.001). Both KVf and KVb were significantly higher in VKC group when compared to the control group.
Children with VKC have significantly higher PCE as measured by Sirius tomographer, and hence, all VKC children should be screened for development of KC and the Sirius tomographer may be an appropriate tool for the same.
这是一项病例对照研究。我们纳入了2019年9月至2020年6月在印度南部三级眼科护理中心儿科眼科门诊就诊的110名儿童。Sirius断层摄影师/地形图师检查了55名VKC儿童和55名正常年龄和性别匹配的儿童(CSO,意大利)确定PCE,最薄角膜厚度(TCT),模拟K(SimK),圆锥角膜前(KVf)和圆锥角膜顶点后(KVb)。比较两组的各项参数。
共检查了110名儿童的220只眼。两组的平均年龄为10.44±3.28岁,每组包括44名男性和11名女性。两组间TCT、SimK差异无统计学意义。VKC组平均PCE为18.8±8.4μm,对照组为11.7±3.9μm(P<0.001)。与对照组相比,VKC组的KVf和KVb均显着较高。
天狼星断层扫描测量的VKC儿童PCE明显较高,因此,所有VKC儿童都应进行KC发育筛查,Sirius断层摄影师可能是一个合适的工具.