Abstract:
We show a description of pregnancy cohorts in the European region. Our investigation identified 66 pregnancy cohorts, mostly hosted in Western Central Europe. Among these 66 cohorts, 24 began recruitment before the year 2000, while six cohorts are still enrolling. The most common topics were lifestyle, environment and nutrition with allergies and neurodevelopment being a minority. We observed a pattern of positive correlations between data collected using medical records, structured interviews, and the collection of biological samples. Objectively assessed data were negatively correlated with self-administered questionnaires. Eight cohorts addressed intrauterine exposure, focusing on environmental pollutants such as endocrine-disrupting chemicals. The effects of these compounds on the developing foetus have been studied greatly, but more research on their effects is still needed. Many cohorts investigated genetics through the collection of biological samples from the mothers and children, to improve knowledge on the mother-to-child transmission of genetic information, antibodies, microbiota, etc. Paediatric epidemiology represents an important field of research since preserving healthy lives from conception onwards is the most efficient way to improve population health. According to our report, it seems that this field of research is well developed in Europe, where numerous high profile studies are currently ongoing.
摘要:
我们显示了欧洲地区妊娠队列的描述。我们的调查确定了66个怀孕队列,主要在中欧西部举办。在这66个队列中,24人在2000年之前开始招募,而6人仍在招募中。最常见的话题是生活方式,环境和营养过敏和神经发育是少数。我们观察到使用医疗记录收集的数据之间存在正相关的模式,结构化面试,和生物样本的收集。客观评估的数据与自我管理的问卷呈负相关。八个队列解决了宫内暴露,关注环境污染物,如干扰内分泌的化学物质。这些化合物对发育中的胎儿的影响已被大量研究,但仍需要对其影响进行更多研究。许多队列通过收集母亲和儿童的生物样本来调查遗传学,提高对母婴传播遗传信息的认识,抗体,微生物群,等。儿科流行病学代表了一个重要的研究领域,因为从受孕开始保持健康的生活是改善人口健康的最有效方法。根据我们的报告,这个研究领域似乎在欧洲很发达,目前正在进行许多备受瞩目的研究。