Abstract：
Danggui Buxue Decoction is a classic prescription of Qi and blood tonification, which is mainly applied in treating fatigue, internal damage Qi weakness, blood deficiency, and outward going of floating Yang. Modern pharmacology shows that it can promote hematopoiesis, regulate immunity, and protect heart and cerebral vessels. The prescription, often used for the treatment of anemia and other diseases in clinic, is composed of Astragali Radix and Angelicae Sinensis Radix at a dosage ratio of 5∶1. It is a modern compound prescription for invigorating Qi and generating blood. Based on the review of the chemical constituents, pharmacological effects, and clinical applications of Danggui Buxue Decoction, its Q-marker was predicted and analyzed according to the "five principles" of Chinese medicine Q-marker--quality transmissibility and traceability, ingredient specificity, component validity, component measurabi-lity, and formula compatibility environment. The results suggested that calycosin, calycosin-7-O-β-D-glucoside, formononetin, ononin, astragaloside A, ferulic acid, and ligustilide could be used as Q-markers of Danggui Buxue Decoction, which provides reference for establishing the quality system of Danggui Buxue Decoction.
摘要：
当归补血汤是经典的益气补血方剂,主要用于治疗疲劳，内伤气虚,血虚,浮阳的向外。现代药理学表明，它可以促进造血，调节免疫力，保护心脏和脑血管.处方，临床上常用于治疗贫血等疾病,由黄芪和当归以5∶1的用量组成。它是一种现代的补气生血复方。在对化学成分进行综述的基础上，药理作用，当归补血汤的临床应用,根据中药Q标记的五项原则——质量传递性和可追溯性，对其Q标记进行了预测和分析，成分特异性，组件有效性，分量可测量性，和配方兼容性环境。结果提示,calycosin-7-O-β-D-葡萄糖苷，福蒙素,ononin,黄芪甲苷,阿魏酸,并可作为当归补血汤的Q标记,为建立当归补血汤的质量体系提供参考。
