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Abstract：
UNASSIGNED: Common surgical techniques aim to turn the entire vomerine mucosa with vomer flaps either to the oral side or to the nasal side. The latter approach is widely performed due to the similarity in color to the nasal mucosa. However, we lack a histologic description of the curved vomerine mucosa in cleft lip and palate malformations.
UNASSIGNED: We histologically examined an excess of curved vomerine mucosa in 8 patients using hematoxylin-eosin, periodic acid-Schiff, Elastin van Gieson, and Alcian blue stains. Tissue samples were obtained during surgery at 8 months of age.
UNASSIGNED: Our histological analysis of the mucoperiosteum overlying the curved vomer revealed characteristics consistent with those of an oral mucosa or a squamous metaplasia of the nasal mucosa, as exhibited by a stratified squamous epithelium containing numerous seromucous glands. Some areas showed a palisaded arrangement of the basal cells compatible with metaplasia of respiratory epithelium, but no goblet cells or respiratory cilia were identified. Abundant fibrosis and rich vascularity were present.
UNASSIGNED: The vomer mucosa showed no specific signs of nasal mucosa. These findings should be considered in presurgical cleft orthopedics and palatal surgery for further refinement. Shifting the vomer mucosa according to a fixed physiologic belief should not overrule other important aspects of cleft repair such as primary healing and establishing optimal form and function of palatal roof and nasal floor.
UNASSIGNED: We histologically examined an excess of curved vomerine mucosa in 8 patients using hematoxylin-eosin, periodic acid-Schiff, Elastin van Gieson, and Alcian blue stains. Tissue samples were obtained during surgery at 8 months of age.
UNASSIGNED: Our histological analysis of the mucoperiosteum overlying the curved vomer revealed characteristics consistent with those of an oral mucosa or a squamous metaplasia of the nasal mucosa, as exhibited by a stratified squamous epithelium containing numerous seromucous glands. Some areas showed a palisaded arrangement of the basal cells compatible with metaplasia of respiratory epithelium, but no goblet cells or respiratory cilia were identified. Abundant fibrosis and rich vascularity were present.
UNASSIGNED: The vomer mucosa showed no specific signs of nasal mucosa. These findings should be considered in presurgical cleft orthopedics and palatal surgery for further refinement. Shifting the vomer mucosa according to a fixed physiologic belief should not overrule other important aspects of cleft repair such as primary healing and establishing optimal form and function of palatal roof and nasal floor.
摘要：
■常见的外科技术旨在将带有中空皮瓣的整个vomerine粘膜转向口腔侧或鼻侧。由于与鼻粘膜的颜色相似，后一种方法被广泛执行。然而,我们缺乏对唇腭裂畸形的弯曲vomerine粘膜的组织学描述。
■我们使用苏木精-伊红对8例患者进行了组织学检查，高碘酸-希夫，ElastinvanGieson,和阿尔西亚的蓝色污渍。在手术期间在8月龄时获得组织样品。
■我们对覆盖在弯曲的子宫上的粘膜骨膜的组织学分析揭示了与口腔粘膜或鼻粘膜鳞状化生一致的特征，表现为包含许多浆膜腺体的复层鳞状上皮。一些区域显示出与呼吸道上皮化生相容的基底细胞的栅栏排列，但没有发现杯状细胞或呼吸道纤毛。存在丰富的纤维化和丰富的血管。
■黏膜无鼻粘膜特异性征象。这些发现应在术前left裂骨科和pa手术中加以考虑，以进一步完善。根据固定的生理信念改变子宫黏膜不应超过裂隙修复的其他重要方面，例如初级愈合以及建立腭顶和鼻底的最佳形式和功能。
■我们使用苏木精-伊红对8例患者进行了组织学检查，高碘酸-希夫，ElastinvanGieson,和阿尔西亚的蓝色污渍。在手术期间在8月龄时获得组织样品。
■我们对覆盖在弯曲的子宫上的粘膜骨膜的组织学分析揭示了与口腔粘膜或鼻粘膜鳞状化生一致的特征，表现为包含许多浆膜腺体的复层鳞状上皮。一些区域显示出与呼吸道上皮化生相容的基底细胞的栅栏排列，但没有发现杯状细胞或呼吸道纤毛。存在丰富的纤维化和丰富的血管。
■黏膜无鼻粘膜特异性征象。这些发现应在术前left裂骨科和pa手术中加以考虑，以进一步完善。根据固定的生理信念改变子宫黏膜不应超过裂隙修复的其他重要方面，例如初级愈合以及建立腭顶和鼻底的最佳形式和功能。
