RHOX10 通过转录因子信号级联驱动小鼠精原干细胞的建立。
关键词: DMRT1 RHOX10 SLAM-seq ZBTB16 gonocyte homeobox pro-spermatogonia single-cell RNA-seq spermatogonial stem cells transcription factor
Mesh : Animals Base Sequence Cell Differentiation / genetics Gene Expression Regulation, Developmental Genome Germ Cells / metabolism HEK293 Cells Homeodomain Proteins / metabolism Humans Male Mice, Inbred C57BL Promyelocytic Leukemia Zinc Finger Protein / metabolism Signal Transduction Spermatogonia / cytology Stem Cells / cytology metabolism Transcription Factors / metabolism Transcription, Genetic Transcriptional Activation / genetics Mice
来 源:
DOI:10.1016/j.celrep.2021.109423
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