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Abstract：
UNASSIGNED: Studies of saccular and utricular function in patients with obstructive sleep apnea (OSA) are rare. We noticed that some OSA patients also had positive results in vestibular function tests, and this inspired our interest in exploring the vestibular function patterns of OSA patients.
UNASSIGNED: To investigate otolithic organ function in severe OSA patients who lack vestibular symptoms and systemic disease.
UNASSIGNED: 32 patients (64 ears) with severe OSA and 22 healthy controls (44 ears) were enrolled. The ocular and cervical vestibular-evoked myogenic potentials (oVEMP and cVEMP) and the caloric test were recorded and analyzed.
UNASSIGNED: The response rates of oVEMP (73.4%) and cVEMP (82.8%) in patients with severe OSA were significantly lower than those in controls. In oVEMP, elevated thresholds (p = .002), decreased n1-p1 amplitudes (p < .001), prolonged n1 latencies (p < .001) were observed. In cVEMP, the elevation of thresholds (p < .001), decrease in p1-n1 amplitudes (p < .001), and n1-p2 amplitudes (p < .001), prolongation of p1 latencies (p = .003) were observed. No significant difference in the caloric test was found between the two groups.
UNASSIGNED: Disappearance or impairment of VEMPs could be observed in patients with severe OSA, and reflects different degrees of impairment in the utricle and saccule.
UNASSIGNED: To investigate otolithic organ function in severe OSA patients who lack vestibular symptoms and systemic disease.
UNASSIGNED: 32 patients (64 ears) with severe OSA and 22 healthy controls (44 ears) were enrolled. The ocular and cervical vestibular-evoked myogenic potentials (oVEMP and cVEMP) and the caloric test were recorded and analyzed.
UNASSIGNED: The response rates of oVEMP (73.4%) and cVEMP (82.8%) in patients with severe OSA were significantly lower than those in controls. In oVEMP, elevated thresholds (p = .002), decreased n1-p1 amplitudes (p < .001), prolonged n1 latencies (p < .001) were observed. In cVEMP, the elevation of thresholds (p < .001), decrease in p1-n1 amplitudes (p < .001), and n1-p2 amplitudes (p < .001), prolongation of p1 latencies (p = .003) were observed. No significant difference in the caloric test was found between the two groups.
UNASSIGNED: Disappearance or impairment of VEMPs could be observed in patients with severe OSA, and reflects different degrees of impairment in the utricle and saccule.
摘要：
■对阻塞性睡眠呼吸暂停（OSA）患者的囊和囊功能的研究很少见。我们注意到一些OSA患者在前庭功能测试中也有阳性结果，这激发了我们探索OSA患者前庭功能模式的兴趣。
■研究缺乏前庭症状和全身性疾病的重度OSA患者的耳石器官功能。
■纳入了32例重度OSA患者（64耳）和22例健康对照（44耳）。记录并分析眼和颈部前庭诱发的肌源性电位（oVEMP和cVEMP）以及热量测试。
■重度OSA患者的oVEMP（73.4％）和cVEMP（82.8％）的缓解率明显低于对照组。在OVEMP中,升高的阈值（p=.002），n1-p1振幅降低（p<.001），观察到延长的n1潜伏期(p<.001)。在cVEMP中，阈值的升高（p<.001），p1-n1振幅降低（p<.001），和n1-p2振幅（p<.001），观察到p1潜伏期延长（p=.003）。两组之间在热量测试中没有发现显着差异。
■在重度OSA患者中可以观察到VEMPs的消失或损害，反映了囊和囊的不同程度的损伤。
■研究缺乏前庭症状和全身性疾病的重度OSA患者的耳石器官功能。
■纳入了32例重度OSA患者（64耳）和22例健康对照（44耳）。记录并分析眼和颈部前庭诱发的肌源性电位（oVEMP和cVEMP）以及热量测试。
■重度OSA患者的oVEMP（73.4％）和cVEMP（82.8％）的缓解率明显低于对照组。在OVEMP中,升高的阈值（p=.002），n1-p1振幅降低（p<.001），观察到延长的n1潜伏期(p<.001)。在cVEMP中，阈值的升高（p<.001），p1-n1振幅降低（p<.001），和n1-p2振幅（p<.001），观察到p1潜伏期延长（p=.003）。两组之间在热量测试中没有发现显着差异。
■在重度OSA患者中可以观察到VEMPs的消失或损害，反映了囊和囊的不同程度的损伤。
