PDF(Pubmed)
Abstract：
Cold agglutinin are erythrocyte antibodies which possess the property of agglutinating red blood cells at temperatures of below 37°C, this phenomenon is reversible after heating. This is usually immunoglobulin M (IgM) class. Their pathogenicity is much more related to their temperature range of activity than their title. As we report in this observation, cold hemagglutination makes it difficult to interpret certain immunological tests such as ABO Rh blood grouping or searching for irregular antibodies (SAI). The discovery of cold agglutinins can be fortuitous revealing itself by disturbances and aberrations in the results of blood count or as part of a suggestive clinical or laboratory table cold hemagglutinin disease. The search for a lymphoid hematological at their diagnosis should be systematic.
摘要：
冷凝集素是红细胞抗体，具有在低于37°C的温度下凝集红细胞的特性，这种现象在加热后是可逆的。这通常是免疫球蛋白M(IgM)类。它们的致病性与它们的活性温度范围比它们的标题更相关。正如我们在本观察中报告的那样，冷血凝使得难以解释某些免疫学测试，例如ABORh血型或寻找不规则抗体（SAI）。冷凝集素的发现可以偶然地通过血细胞计数结果的干扰和畸变或作为提示临床或实验室表的冷血凝素疾病的一部分来揭示自身。在诊断时寻找淋巴血液学应该是系统的。
