Role of proton therapy in reirradiation and in the treatment of sarcomas.

质子治疗在再照射和肉瘤治疗中的作用。

• 影响指数: 1.217
• 发表时间: Oct 2021
• 来源期刊: Cancer Radiother
• DOI: 10.1016/j.canrad.2021.06.024
• PMID: 34284969
• 文章类型: Journal Article
• 中科院分区: Q4
• 方向: 医学
• 作者列表: Doyen J,Aloi D,Groulier A,Vidal M,Lesueur P,Calugaru V,Bondiau PY

关键词: Proton Therapy; Protonthérapie; Reirradiation; Réirradiation; Sarcoma; Sarcome

Mesh: Humans; Neoplasm Recurrence, Local / radiotherapy; Neoplasms, Second Primary / radiotherapy; Proton Therapy / adverse effects; Radiation Tolerance; Re-Irradiation / adverse effects methods; Sarcoma / radiotherapy

Abstract

Reirradiation and irradiation of sarcoma is often difficult due to the frequent need for a high dose of radiation in order to increase tumor control. This can result in a greater risk of toxicity which can be mitigated with the use of proton therapy. The present review aims to summarize the role of proton therapy in these 2 clinical contexts.

摘要

由于经常需要高剂量的辐射以增加肿瘤控制，因此肉瘤的再辐射和辐射通常很困难。这可以导致更大的毒性风险,其可以通过使用质子疗法来减轻。本综述旨在总结质子治疗在这两种临床环境中的作用。