Abstract：
OBJECTIVE: Coronavirus disease 2019 is responsible for a worldwide increase in morbidity and mortality. The relationship of this infection to mother-to-child vertical transmission has not been elucidated yet. However, recent reports indicate a foetal death rate of up to 3%.
METHODS: We report a case of sudden pre-term foetal demise in a woman positive for SARS-CoV-2 but asymptomatic, with physiological course of pregnancy.
RESULTS: One of the possible explanations of sudden foetal death may be acute placental insufficiency caused by a SARS-CoV-2 placental infection or the development of foetal inflammatory response syndrome (FIRS).
CONCLUSIONS: Considering the potential risk of foetal demise, questions remain regarding foetal monitoring and the timing of labour and delivery in the second and third trimesters, particularly in asymptomatic or mild maternal SARS-CoV-2 infection. A relevant multidisciplinary team must also be aware of these risks associated with possibly fatal consequences.
METHODS: We report a case of sudden pre-term foetal demise in a woman positive for SARS-CoV-2 but asymptomatic, with physiological course of pregnancy.
RESULTS: One of the possible explanations of sudden foetal death may be acute placental insufficiency caused by a SARS-CoV-2 placental infection or the development of foetal inflammatory response syndrome (FIRS).
CONCLUSIONS: Considering the potential risk of foetal demise, questions remain regarding foetal monitoring and the timing of labour and delivery in the second and third trimesters, particularly in asymptomatic or mild maternal SARS-CoV-2 infection. A relevant multidisciplinary team must also be aware of these risks associated with possibly fatal consequences.
摘要：
目标：2019年冠状病毒病是全球发病率和死亡率上升的原因。这种感染与母婴垂直传播的关系尚未阐明。然而,最近的报告显示胎儿死亡率高达3%。
方法：我们报告一例SARS-CoV-2阳性但无症状的女性早产胎儿突然死亡，生理上的怀孕过程。
结果：胎儿猝死的可能解释之一可能是SARS-CoV-2胎盘感染引起的急性胎盘功能不全或胎儿炎症反应综合征（FIRS）的发展。
结论：考虑到胎儿死亡的潜在风险，关于胎儿监测以及第二和第三个三个月的分娩和分娩时间仍然存在问题，特别是在无症状或轻度孕产妇SARS-CoV-2感染中。相关的多学科团队还必须意识到与可能致命的后果相关的这些风险。
方法：我们报告一例SARS-CoV-2阳性但无症状的女性早产胎儿突然死亡，生理上的怀孕过程。
结果：胎儿猝死的可能解释之一可能是SARS-CoV-2胎盘感染引起的急性胎盘功能不全或胎儿炎症反应综合征（FIRS）的发展。
结论：考虑到胎儿死亡的潜在风险，关于胎儿监测以及第二和第三个三个月的分娩和分娩时间仍然存在问题，特别是在无症状或轻度孕产妇SARS-CoV-2感染中。相关的多学科团队还必须意识到与可能致命的后果相关的这些风险。
