Abstract:
Greater superficial petrosal nerve (GSPN) schwannomas are an exceedingly rare nerve sheath tumor. The current literature search was conducted using Medline and Embase database by key search terms. Only 31 cases have been reported in the literature so far. Facial palsy, hearing loss, and xerophthalmia accounted for 48.4% (15), 41.9% (13), and 29% (9) of all cases, respectively. The middle cranial fossa approach was used in all previous reports. A retrospective review of 2 GSPN schwannomas patients treated by endoscopic endonasal approach (EEA) in our center was collected. Clinical records, including clinical features, pre- and postoperative images, surgery, and follow-up information, were reviewed. In all cases, clinical features including facial numbness and headache were found, with tinnitus in case 1, hearing loss, xerophthalmia in case 2. Imaging studies showed a solid mass that originated in the anterior of the petrous bone. Two patients were treated by EEA. Furthermore, no recurrence was found during the follow-up period (15-29 months) in both of the 2 cases after the operation. Complete resection of GSPN schwannomas can be achieved via the pure EEA. Endoscopic endonasal approach for radical removal of tumors is safe and feasible.
摘要:
大岩浅神经(GSPN)神经鞘瘤是一种极为罕见的神经鞘瘤。目前的文献检索使用Medline和Embase数据库按关键检索术语进行。到目前为止,文献中仅报告了31例。面神经麻痹,听力损失,干眼症占48.4%(15),41.9%(13),所有病例的29%(9),分别。以前的所有报告均使用中颅窝入路。收集了我们中心2例经鼻内镜入路(EEA)治疗的GSPN神经鞘瘤患者的回顾性研究。临床记录,包括临床特征,术前和术后图像,手术,和后续信息,被审查了。在所有情况下,发现了包括面部麻木和头痛在内的临床特征,有耳鸣的情况1,听力损失,病例2中的干眼症。影像学研究显示,固体肿块起源于岩骨的前部。两名患者接受EEA治疗。此外,2例患者术后随访15~29个月,均未发现复发。GSPN神经鞘瘤的完全切除可以通过纯EEA实现。经鼻内镜下根治性切除肿瘤是安全可行的。