Abstract:
Since the first Oxford Survey of Childhood Cancer\'s results were published, people have become more aware of the risks associated with prenatal exposure from diagnostic x rays. As a result, it has since been the subject of many studies. In this review, the results of recent epidemiological studies are summarized. The current international guidelines for diagnostic x-ray examinations were compared to the review. All epidemiological studies starting from 2007 and all relevant international guidelines were included. Apart from one study that involved rhabdomyosarcoma, no statistically significant associations were found between prenatal exposure to x rays and the development of cancer during 2007-2020. Most of the studies were constrained in their design due to too small a cohort or number of cases, minimal x-ray exposure, and/or data obtained from the exposed mothers instead of medical reports. In one of the studies, computed tomography exposure was also included, and this requires more and longer follow-up in successive studies. Most international guidelines are comparable, provide risk coefficients that are quite conservative, and discourage abdominal examinations of pregnant women.
摘要:
自从第一次牛津儿童癌症调查的结果发表以来,人们越来越意识到与诊断x射线产前暴露相关的风险。因此,此后,它一直是许多研究的主题。在这次审查中,总结了最近的流行病学研究结果。将当前的国际诊断X射线检查指南与该综述进行了比较。从2007年开始的所有流行病学研究和所有相关的国际指南都包括在内。除了一项涉及横纹肌肉瘤的研究,在2007-2020年间,未发现产前x光暴露与癌症发展之间有统计学意义的关联.由于队列或病例数量太小,大多数研究在设计上受到限制,最小的x射线照射,和/或从暴露母亲那里获得的数据,而不是医疗报告。在其中一项研究中,计算机断层扫描曝光也包括在内,这需要在连续研究中进行越来越多的随访。大多数国际准则具有可比性,提供相当保守的风险系数,并阻止孕妇的腹部检查。