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Abstract：
UNASSIGNED: Aging is associated with progressive loss of musculoskeletal performance. Exercise interventions can improve physical function in the elderly but there is a paucity of comparative assessments in order to understand what specific goals can be achieved particularly with less demanding exercise interventions readily accessible for untrained men.
UNASSIGNED: Prospective randomized, controlled, single center exploratory trial to compare four distinct exercise interventions, i.e. Resistance Training (RT), Whole Body Vibration Exercise (WBV), Qi Gong (QG) and wearing a Spinal orthosis (SO) for 6 months in men at risk for osteoporosis aged 65-90 years. Primary endpoint was change in isometric one repetition maximum force trunk strength for extension (TSE) and flexion (TSF) compared to baseline, secondary endpoints covered key parameters of geriatric functional assessment, including Handgrip Strength (HS), Chair-Rise-Test (CRT), Usual Gait Speed (UGS) and Timed-Up-and-Go (TUG).
UNASSIGNED: Altogether 47 men (mean age 77 ±6.1 years) were randomized to RT, (n = 11) WBV (n = 13), QG (n = 10) and SO(n = 13). RT, defined as reference exercise intervention, lead to significant improvements for TSE (p = 0.009) and TSF (p = 0.013) and was significantly superior in the between-group analysis for TSE (p = 0.038). Vibration exercise caused sign. Improvements in TSE (p = 0.014) and CRT (p = 0.005), the Spinal orthosis improved CRT (p = 0.003) and Gait Speed (p = 0.027), while the QG intervention did not attain any sig. Developments.Subgroup analyses revealed most pronounced musculoskeletal progress in vulnerable patients (age ≥ 80 years, pre-sarcopenia, multimorbidity ≥3chronic diseases). Irrespective of the type of exercise, participants ≥80 years experienced significant gains in TSE (p = 0.029) and CRT (p = 0.017). Presarcopenic subjects (Skeletal muscle Index (SMI) ≤10.75 kg/m2) improved in TSE (p = 0.003), CRT (p = 0.001) and UGS (p = 0.016). Multimorbid participants achieved sig. Gains in TSE (p < 0.001), TSF (p = 0.002), UGS (p = 0.036) and HS (p = 0.046).
UNASSIGNED: In this exploratory trial we found that simple exercise interventions are feasible in elderly men eliciting specific benefits, i.e. improvements are attained in those tasks addressed with the respective exercise modality. While targeted resistance training is superior in increasing TSE, alternative simple exercise interventions also appear to elicit beneficial effects, even in vulnerable patients, i.e. those with low muscle mass, above 80 years of age or multimorbidity.
UNASSIGNED: Prospective randomized, controlled, single center exploratory trial to compare four distinct exercise interventions, i.e. Resistance Training (RT), Whole Body Vibration Exercise (WBV), Qi Gong (QG) and wearing a Spinal orthosis (SO) for 6 months in men at risk for osteoporosis aged 65-90 years. Primary endpoint was change in isometric one repetition maximum force trunk strength for extension (TSE) and flexion (TSF) compared to baseline, secondary endpoints covered key parameters of geriatric functional assessment, including Handgrip Strength (HS), Chair-Rise-Test (CRT), Usual Gait Speed (UGS) and Timed-Up-and-Go (TUG).
UNASSIGNED: Altogether 47 men (mean age 77 ±6.1 years) were randomized to RT, (n = 11) WBV (n = 13), QG (n = 10) and SO(n = 13). RT, defined as reference exercise intervention, lead to significant improvements for TSE (p = 0.009) and TSF (p = 0.013) and was significantly superior in the between-group analysis for TSE (p = 0.038). Vibration exercise caused sign. Improvements in TSE (p = 0.014) and CRT (p = 0.005), the Spinal orthosis improved CRT (p = 0.003) and Gait Speed (p = 0.027), while the QG intervention did not attain any sig. Developments.Subgroup analyses revealed most pronounced musculoskeletal progress in vulnerable patients (age ≥ 80 years, pre-sarcopenia, multimorbidity ≥3chronic diseases). Irrespective of the type of exercise, participants ≥80 years experienced significant gains in TSE (p = 0.029) and CRT (p = 0.017). Presarcopenic subjects (Skeletal muscle Index (SMI) ≤10.75 kg/m2) improved in TSE (p = 0.003), CRT (p = 0.001) and UGS (p = 0.016). Multimorbid participants achieved sig. Gains in TSE (p < 0.001), TSF (p = 0.002), UGS (p = 0.036) and HS (p = 0.046).
UNASSIGNED: In this exploratory trial we found that simple exercise interventions are feasible in elderly men eliciting specific benefits, i.e. improvements are attained in those tasks addressed with the respective exercise modality. While targeted resistance training is superior in increasing TSE, alternative simple exercise interventions also appear to elicit beneficial effects, even in vulnerable patients, i.e. those with low muscle mass, above 80 years of age or multimorbidity.
摘要：
■衰老与肌肉骨骼性能的进行性丧失有关。运动干预措施可以改善老年人的身体功能，但缺乏比较评估，以了解可以实现哪些具体目标，特别是要求不高的运动干预措施可供未经训练的男性使用。
■前瞻性随机，控制,单中心探索性试验，比较四种不同的运动干预措施，即阻力训练（RT），全身振动运动（WBV），气功（QG）和佩戴脊柱矫形器（SO）6个月在65-90岁有骨质疏松症风险的男性中。主要终点是与基线相比，等距一次重复的最大力干伸展强度（TSE）和屈曲强度（TSF）的变化，次要终点涵盖老年功能评估的关键参数，包括手柄强度（HS），椅子上升测试（CRT），通常的步态速度（UGS）和定时上升和运行（TUG）。
■共有47名男性（平均年龄77±6.1岁）被随机分配到RT，（n=11）WBV（n=13），QG(n=10)和SO(n=13)。RT,定义为参考运动干预，导致TSE(p=0.009)和TSF(p=0.013)显著改善,并且在TSE的组间分析中显著优于TSE(p=0.038).振动运动引起的征兆。TSE（p=0.014）和CRT（p=0.005）的改进，脊柱矫形器改善了CRT（p=0.003）和步态速度（p=0.027），而QG干预没有达到任何sig。事态发展。亚组分析显示，脆弱患者的肌肉骨骼进展最明显（年龄≥80岁，肌少症前期,多发病率≥3慢性病)。无论运动类型如何，≥80岁的参与者在TSE(p=0.029)和CRT(p=0.017)方面有显著的改善.Presarcopencomesubjects(Skeleticmuscleindex(SMI)≤10.75kg/m2)improvedinTSE(p=0.003),CRT（p=0.001）和UGS（p=0.016）。多方参与者取得了成功。TSE收益（p<0.001），TSF（p=0.002），UGS(p=0.036)和HS(p=0.046)。
■在这项探索性试验中，我们发现简单的运动干预措施对老年男性是可行的，可以带来特定的益处，即在用各自的锻炼方式解决的那些任务中实现了改进。虽然有针对性的阻力训练在增加TSE方面具有优势，替代简单的运动干预措施也似乎会产生有益的效果，即使是脆弱的病人，即那些肌肉质量低的人，80岁以上或多发病。
■前瞻性随机，控制,单中心探索性试验，比较四种不同的运动干预措施，即阻力训练（RT），全身振动运动（WBV），气功（QG）和佩戴脊柱矫形器（SO）6个月在65-90岁有骨质疏松症风险的男性中。主要终点是与基线相比，等距一次重复的最大力干伸展强度（TSE）和屈曲强度（TSF）的变化，次要终点涵盖老年功能评估的关键参数，包括手柄强度（HS），椅子上升测试（CRT），通常的步态速度（UGS）和定时上升和运行（TUG）。
■共有47名男性（平均年龄77±6.1岁）被随机分配到RT，（n=11）WBV（n=13），QG(n=10)和SO(n=13)。RT,定义为参考运动干预，导致TSE(p=0.009)和TSF(p=0.013)显著改善,并且在TSE的组间分析中显著优于TSE(p=0.038).振动运动引起的征兆。TSE（p=0.014）和CRT（p=0.005）的改进，脊柱矫形器改善了CRT（p=0.003）和步态速度（p=0.027），而QG干预没有达到任何sig。事态发展。亚组分析显示，脆弱患者的肌肉骨骼进展最明显（年龄≥80岁，肌少症前期,多发病率≥3慢性病)。无论运动类型如何，≥80岁的参与者在TSE(p=0.029)和CRT(p=0.017)方面有显著的改善.Presarcopencomesubjects(Skeleticmuscleindex(SMI)≤10.75kg/m2)improvedinTSE(p=0.003),CRT（p=0.001）和UGS（p=0.016）。多方参与者取得了成功。TSE收益（p<0.001），TSF（p=0.002），UGS(p=0.036)和HS(p=0.046)。
■在这项探索性试验中，我们发现简单的运动干预措施对老年男性是可行的，可以带来特定的益处，即在用各自的锻炼方式解决的那些任务中实现了改进。虽然有针对性的阻力训练在增加TSE方面具有优势，替代简单的运动干预措施也似乎会产生有益的效果，即使是脆弱的病人，即那些肌肉质量低的人，80岁以上或多发病。
